Visions for regenerative medicine: Interface between scientific fact and science fiction

被引：23

作者：

Kirkpatrick, C. James ^{[1
]}

Fuchs, Sabine ^{[1
]}

Peters, Kirsten ^{[1
]}

Brochhausen, Christoph ^{[1
]}

Hermanns, M. Iris ^{[1
]}

Unger, Ronald E. ^{[1
]}

机构：

[1] Univ Mainz, Inst Pathol, REPAIR Lab, D-55101 Mainz, Germany

来源：

ARTIFICIAL ORGANS | 2006年 / 30卷 / 10期

关键词：

regenerative medicine; materials sciences; life sciences; intelligent materials-stem cells; drug delivery; gene therapy;

D O I：

10.1111/j.1525-1594.2006.00306.x

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This article gives a brief overview of the authors' views on the future development of tissue engineering with respect to the challenges both to the materials and life sciences. Emphasis will be placed on the advantages of three-dimensional bioresorbable polymers in combination with relevant molecular cues and the application of autologous stem or progenitor cells. There is a requirement for much more diversity in the synthesis of so-called "intelligent" materials, which respond to external stimuli, as well as the development of novel drug and gene delivery systems. In addition, much more basic research is necessary in developmental biology and the application of modern cell and molecular biology to biomaterial questions.

引用

页码：822 / 827

页数：6

共 36 条

[1] Gene expression perturbation in vitro - A growing case for three-dimensional (3D) culture systems [J].