Postantibiotic effect of trovafloxacin on Pseudomonas aeruginosa

被引：15

作者：

Boswell, FJ

Andrews, JM

Wise, R

机构：

[1] Department of Medical Microbiology, City Hospital NHS Trust, Birmingham B18 7QH, Dudley Road

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1997年 / 39卷 / 06期

关键词：

D O I：

10.1093/jac/39.6.811

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The postantibiotic effect (PAE) of trovafloxacin (CP 99,219) was investigated with six strains of Pseudomonas aeruginosa at concentrations equivalent to 0.5, 1, 2 and 4 x MIC. Trovafloxacin exhibited a significant PAE with four out of the six strains of P. aeruginosa studied. The PAE values obtained for trovafloxacin with P. aeruginosa ranged from 0.3 h to 2.3 h, increasing with increased exposure time and trovafloxacin concentration.

引用

页码：811 / 814

页数：4

共 9 条

[1]

[Anonymous], 1991, J Antimicrob Chemother, V27 Suppl D, P1

[2] Bactericidal activity of trovafloxacin under anaerobic and aerobic conditions [J].