Metformin monotherapy in melanoma: a pilot, open-label, prospective, and multicentric study indicates no benefit

被引：33

作者：

Montaudie, Henri ^{[1
,2
]}

Cerezo, Michael ^{[3
]}

Bahadoran, Philippe ^{[1
,4
]}

Roger, Coralie ^{[5
]}

Passeron, Thierry ^{[1
,2
]}

Machet, Laurent ^{[6
]}

Arnault, Jean-Philippe ^{[7
]}

Verneuil, Laurence ^{[8
]}

Maubec, Eve ^{[9
]}

Aubin, Francois ^{[10
]}

Granel, Florence ^{[11
]}

Giacchero, Damien ^{[12
]}

Hofman, Veronique ^{[13
,14
]}

Lacour, Jean-Philippe ^{[1
]}

Maryline, Allegra ^{[3
]}

Ballotti, Robert ^{[3
]}

Rocchi, Stephane ^{[3
]}

机构：

[1] Univ Hosp Nice, Dept Dermatol, Nice, France

[2] INSERM, Ctr Mediterran Med Mol, U1065, Nice, France

[3] INSERM, Ctr Mediterran Med Mol, U1065, Team 1, Nice, France

[4] Archet Hosp, Clin Res Ctr, Dept Dermatol, Nice, France

[5] Univ Hosp Nice, Dept Clin Res & Innovat, Nice, France

[6] Univ Francois Rabelais Tours, Dept Dermatol, CHRU Tours, Tours, France

[7] Univ Hosp Amiens, Dept Dermatol, Amiens, France

[8] Univ Hosp Caen, Dept Dermatol, Caen, France

[9] Hosp Bichat, Univ Hosp Paris, Dept Dermatol, Nice, France

[10] Univ Hosp Besancon, Dept Dermatol, Besancon, France

[11] Univ Hosp Nancy, Dept Dermatol, Nancy, France

[12] Univ Nice Sophia, Antoine Lacassagne Canc Ctr, Dept Oncol, Nice, France

[13] Nice Univ Hosp, Lab Clin & Expt Pathol & Human Biobank, Nice, France

[14] Univ Nice Sophia Antipolis, Fac Med, INSERM 1081, IRCAN,Team 3, Nice, France

来源：

PIGMENT CELL & MELANOMA RESEARCH | 2017年 / 30卷 / 03期

关键词：

DOUBLE-BLIND; CANCER; COMBINATION; TRAMETINIB; THERAPY; PLACEBO; TRIAL;

D O I：

10.1111/pcmr.12576

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

引用

页码：378 / 380

页数：3

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