Surveillance guidelines after removal of colorectal adenomatous polyps

被引:251
作者
Atkin, WS [1 ]
Saunders, BP
机构
[1] St Marks Hosp, Canc Res UK Colorectal Canc Unit, Harrow HA1 3UJ, Middx, England
[2] St Marks Hosp, Wolfson Unit Endoscopy, Harrow HA1 3UJ, Middx, England
关键词
D O I
10.1136/gut.51.suppl_5.v6
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Most colon cancers are assumed to have a premalignant adenomatous polyp phase, therefore colonoscopic detection and polypectomy provides the opportunity for cancer prevention. Some patients who have undergone colonoscopy and have had adenomas removed are at increased risk of developing colorectal cancer (CRC) in the future, and therefore might benefit from colonoscopic surveillance. However, it is important to appreciate that colonoscopy is an invasive and costly procedure with some associated morbidity. It is also an under-resourced procedure in the UK, with a serious lack of fully trained endoscopists. Around one third of the population will develop an adenoma by age 60. Most adenomas are asymptomatic and remain undiagnosed. If colorectal screening is introduced this situation will change dramatically. There arc few data on the benefits of colonoscopic surveillance in preventing cotorectal cancer after a baseline clearing colonoscopy. It is therefore important that this practice is applied judiciously, balancing the risks and benefits in each individual case. Using published evidence, this guideline recommends appropriate surveillance after adenoma removal. The decision to perform each follow up colonoscopy should also depend on the patient's wishes, the presence of comorbidity, the patient's age, and the presence of other risk factors.
引用
收藏
页码:V6 / V9
页数:4
相关论文
共 53 条
[1]  
ATKIN W, 1992, GUT, V33, pS52
[2]   LONG-TERM RISK OF COLORECTAL-CANCER AFTER EXCISION OF RECTOSIGMOID ADENOMAS [J].
ATKIN, WS ;
MORSON, BC ;
CUZICK, J .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 326 (10) :658-662
[3]   Significance of a normal surveillance colonoscopy in patients with a history of adenomatous polyps [J].
Blumberg, D ;
Opelka, FG ;
Hicks, TC ;
Timmcke, AE ;
Beck, DE .
DISEASES OF THE COLON & RECTUM, 2000, 43 (08) :1084-1091
[4]  
ECKARDT VF, 1988, CANCER, V61, P2552, DOI 10.1002/1097-0142(19880615)61:12<2552::AID-CNCR2820611227>3.0.CO
[5]  
2-6
[6]   RISK OF COLORECTAL-CANCER IN ADENOMA-BEARING INDIVIDUALS WITHIN A DEFINED POPULATION [J].
EIDE, TJ .
INTERNATIONAL JOURNAL OF CANCER, 1986, 38 (02) :173-176
[7]   Flat adenomas in the United Kingdom: Are treatable cancers being missed? [J].
Fujii, T ;
Rembacken, BJ ;
Dixon, MF ;
Yoshida, S ;
Axon, ATR .
ENDOSCOPY, 1998, 30 (05) :437-443
[8]   Flat adenomas exist in asymptomatic people: important implications for colorectal cancer screening programmes [J].
Hart, AR ;
Kudo, S ;
Mackay, EH ;
Mayberry, JF ;
Atkin, WS .
GUT, 1998, 43 (02) :229-231
[9]   PROSPECTIVE-STUDY OF THE FREQUENCY AND SIZE DISTRIBUTION OF POLYPS MISSED BY COLONOSCOPY [J].
HIXSON, LJ ;
FENNERTY, MB ;
SAMPLINER, RE ;
MCGEE, D ;
GAREWAL, H .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1990, 82 (22) :1769-1772
[10]   PROSPECTIVE BLINDED TRIAL OF THE COLONOSCOPIC MISS-RATE OF LARGE COLORECTAL POLYPS [J].
HIXSON, LJ ;
FENNERTY, MB ;
SAMPLINER, RE ;
GAREWAL, HS .
GASTROINTESTINAL ENDOSCOPY, 1991, 37 (02) :125-127