Clopidogrel and the Concept of High-Risk Pharmacokinetics

被引：53

作者：

Roden, Dan M.

Stein, C. Michael

机构：

[1] Vanderbilt Univ, Dept Med, Sch Med, Nashville, TN 37232 USA

[2] Vanderbilt Univ, Dept Pharmacol, Sch Med, Nashville, TN 37232 USA

来源：

CIRCULATION | 2009年 / 119卷 / 16期

关键词：

Editorials; clopidogrel; pharmacokinetics; pharmacogenetics; CYTOCHROME-P450; 2D6; ANTIPLATELET ACTION; ADJUVANT TAMOXIFEN; MAJOR DETERMINANT; METABOLISM; OMEPRAZOLE; PHARMACOGENOMICS; POLYMORPHISMS; MECHANISM; QUINIDINE;

D O I：

10.1161/CIRCULATIONAHA.109.865907

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2127 / 2130

页数：4

共 31 条

[1]

Ablin Jacob, 2004, Eur J Intern Med, V15, P22, DOI 10.1016/j.ejim.2003.10.004

[2] Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications [J].

Aithal, GP ;

Day, CP ;

Kesteven, PJL ;

Daly, AK .

LANCET, 1999, 353 (9154) :717-719

[3]

AUBERT RE, 2008, 2008 AM HEART ASS SC

[4] ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use A Report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents [J].

Bhatt, Deepak L. ;

Scheiman, James ;

Abraham, Neena S. ;

Antman, Elliott M. ;

Chan, Francis K. L. ;

Furberg, Curt D. ;

Johnson, David A. ;

Mahaffey, Kenneth W. ;

Quigley, Eamonn M. .

CIRCULATION, 2008, 118 (18) :1894-1909

[5]

Caraco Y, 1999, J PHARMACOL EXP THER, V290, P413

[6] Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study [J].

Collet, Jean-Philippe ;

Hulot, Jean-Sebastien ;

Pena, Anna ;

Villard, Eric ;

Esteve, Jean-Baptiste ;

Silvain, Johanne ;

Payot, Laurent ;

Brugier, Delphine ;

Cayla, Guillaume ;

Beygui, Farzin ;

Bensimon, Gilbert ;

Funck-Brentano, Christian ;

Montalescot, Gilles .

LANCET, 2009, 373 (9660) :309-317

[7]

DUNN SP, 2008, 2008 AM HEART ASS SC

[8] Inhibition of P-glycoprotein-mediated drug transport - A unifying mechanism to explain the interaction between digoxin and quinidine [J].

Fromm, MF ;

Kim, RB ;

Stein, CM ;

Wilkinson, GR ;

Roden, DM .

CIRCULATION, 1999, 99 (04) :552-557

[9] Effect of genetic differences in omeprazole metabolism on cure rates for Helicobacter pylori infection and peptic ulcer [J].

Furuta, T ;

Ohashi, K ;

Kamata, T ;

Takashima, M ;

Kosuge, K ;

Kawasaki, T ;

Hanai, H ;

Kubota, T ;

Ishizaki, T ;

Kaneko, E .

ANNALS OF INTERNAL MEDICINE, 1998, 129 (12) :1027-1030

[10]

Gaston Cindy, 2008, Clin Adv Hematol Oncol, V6, P825

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