Lumbar catheterization of the subarachnoid space with a 32-gauge polyurethane catheter in the rat

被引：92

作者：

Pogatzki, EM ^{[1
]}

Zahn, PK ^{[1
]}

Brennan, TJ ^{[1
]}

机构：

[1] Univ Iowa, Coll Med, Dept Anesthesia, Iowa City, IA 52242 USA

来源：

EUROPEAN JOURNAL OF PAIN | 2000年 / 4卷 / 01期

关键词：

intrathecal; pain; spinal cord;

D O I：

10.1053/eujp.1999.0157

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Chronic catheterization of the subarachnoid space of rats is an important tool for intrathecal drug delivery in pharmacologic investigations of pain. We describe a technique using direct lumbar insertion of a small 32-gauge polyurethane (PU) catheter without extensive surgery. Location of the catheter was confirmed with 2% lidocaine injection 1 day later, and methylene blue injection after 7-14 days. This method improved recovery of the rat after catheter implantation and reduced neurologic complications. (C) 2000 European Federation of Chapters of the International Association for the Study of Pain.

引用

页码：111 / 113

页数：3

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