Evaluation of initial CD4+ T cell counts in individuals with newly diagnosed human immunodeficiency virus infection, by sex and race, in urban settings

被引:59
作者
Dybul, M
Bolan, R
Condoluci, D
Cox-Iyamu, R
Redfield, R
Hallahan, CW
Folino, M
Sathasivam, K
Weisberg, M
Andrews, M
Hidalgo, B
Vasquez, J
Fauci, AS
机构
[1] NIAID, Immunoregulat Lab, NIH, Bethesda, MD 20892 USA
[2] Univ Maryland, Inst Human Virol, Baltimore, MD 21201 USA
[3] LA Gay & Lesbian Ctr, Lambda Med Grp, Jeffrey Goodman Special Care Program Clin, Los Angeles, CA USA
[4] Garden State Infect Dis Associates Clin, Voorhees, NJ USA
[5] Whitman Walker Clin, Washington, DC USA
关键词
D O I
10.1086/340650
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The CD4(+) T cell count is an important determinant of disease stage and prognosis in human immunodeficiency virus (HIV)-infected individuals. This study evaluated the CD4(+) T cell counts in individuals at the time of diagnosis of HIV infection at 4 community clinics in large urban settings with relatively high frequencies of HIV infection. Of 2223 individuals, 57% and 36% had CD4(+) T cell counts, 350 and, 200 cells/mm(3), respectively, at the time of diagnosis. There were no clear differences by sex or race. Enhanced educational efforts regarding the importance of HIV testing for at-risk individuals across sex and race strata in community settings may be important for early identification of individuals with HIV infection. This in turn could impact efforts to reduce transmission, and it could impact the prognosis for patients who receive antiretroviral therapy.
引用
收藏
页码:1818 / 1821
页数:4
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