Tracheal resection in the morbidly obese patient: the role of dexmedetomidine

被引:30
作者
Ramsay, Michael A. E. [1 ]
Saha, Devi
Hebeler, Robert F.
机构
[1] Baylor Univ, Med Ctr, Dept Anesthesiol & Pain Management, Dallas, TX 75246 USA
[2] Univ Texas, SW Med Sch, Dept Anesthesiol & Pain Management, Dallas, TX 75246 USA
[3] Baylor Univ, Med Ctr, Dept Cardiothorac Surg, Dallas, TX 75246 USA
关键词
airway; compromise; alpha(2) adrenergic agonist; dexmedetomidine; morbid obesity; sleep apnea; respiration; depression; surgery; trachea resection;
D O I
10.1016/j.jclinane.2006.02.004
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
We present a case of respiratory distress in a morbidly obese woman, which was complicated by a severe tracheal stenosis of the third to sixth cartilage. She had a history of sleep apnea and could only breathe sitting upright. An anesthetic, technique using dexmedetomidine was selected because of its properties of anxiolysis and sedation, with lack of respiratory depression. No intraoperative or postoperative opioids were required. Dexmedetomidine in high doses offers another approach to managing the patient with a compromised airway. Opioids were avoided in this patient, who was at major risk of postoperative respiratory depression and sleep apnea. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:452 / 454
页数:3
相关论文
共 9 条
[1]  
AHO M, 1992, ANESTH ANALG, V75, P940
[2]   A comparison of patient state index and bispectral index values during the perioperative period [J].
Chen, XG ;
Tang, J ;
White, PF ;
Wender, RH ;
Ma, H ;
Sloninsky, A ;
Kariger, R .
ANESTHESIA AND ANALGESIA, 2002, 95 (06) :1669-1674
[3]   Patient state index - Titration of delivery and recovery from propofol, alfentanil, and nitrous oxide anesthesia [J].
Drover, DR ;
Lemmens, HJ ;
Pierce, ET ;
Plourde, G ;
Loyd, G ;
Ornstein, E ;
Prichep, LS ;
Chabot, RJ ;
Gugino, L .
ANESTHESIOLOGY, 2002, 97 (01) :82-89
[4]   The effects of increasing plasma concentrations of dexmedetomidine in humans [J].
Ebert, TJ ;
Hall, JE ;
Barney, JA ;
Uhrich, TD ;
Colinco, MD .
ANESTHESIOLOGY, 2000, 93 (02) :382-394
[5]   Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions [J].
Hall, JE ;
Uhrich, TD ;
Barney, JA ;
Arain, SR ;
Ebert, TJ .
ANESTHESIA AND ANALGESIA, 2000, 90 (03) :699-705
[6]   Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. 1: Pharmacodynamic and pharmacokinetic interactions [J].
Khan, ZP ;
Munday, IT ;
Jones, RM ;
Thornton, C ;
Mant, TG ;
Amin, D .
BRITISH JOURNAL OF ANAESTHESIA, 1999, 83 (03) :372-380
[7]  
Ramsay MAE, 2004, ANESTHESIOLOGY, V101, P787
[8]   Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine [J].
Talke, P ;
Richardson, CA ;
Scheinin, M ;
Fisher, DM .
ANESTHESIA AND ANALGESIA, 1997, 85 (05) :1136-1142
[9]   Respiratory effects of dexmedetomidine in the surgical patient requiring intensive care [J].
Venn, RM ;
Hell, J ;
Grounds, RM .
CRITICAL CARE, 2000, 4 (05) :302-308