Rational design of asymmetric organocatalysts - increased reactivity and solvent scope with a tetrazolic acid

被引：225

作者：

Hartikka, A ^{[1
]}

Arvidsson, PI ^{[1
]}

机构：

[1] Dept Chem, SE-75124 Uppsala, Sweden

来源：

TETRAHEDRON-ASYMMETRY | 2004年 / 15卷 / 12期

关键词：

D O I：

10.1016/j.tetasy.2004.04.029

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Replacement of the carboxylic acid functionality in the widely used organocatalyst proline with a tetrazolic acid leads to a catalyst with increased reactivity and solvent scope, as demonstrated in the direct catalytic asymmetric aldol reaction. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：1831 / 1834

页数：4

共 35 条

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