Mg2+-Mn2+ clusters in enzyme-catalyzed phosphoryl-transfer reactions

被引:94
作者
Tari, LW
Matte, A
Goldie, H
Delbaere, LTJ
机构
[1] UNIV SASKATCHEWAN,DEPT BIOCHEM,SASKATOON,SK S7N 5E5,CANADA
[2] UNIV SASKATCHEWAN,DEPT MICROBIOL,SASKATOON,SK S7N 5E5,CANADA
关键词
D O I
10.1038/nsb1297-990
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Here we show how Mg2+ and Mn2+ function in Escherichia coli phosphoenolpyruvate carboxykinase (PCK) and we propose a general model for the role of binuclear metal clusters in enzyme-catalyzed phosphoryl-transfer reactions.
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收藏
页码:990 / 994
页数:5
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