A 30-year-old body builder with septic shock and ARDS by abuse of anabolic steroids

被引：8

作者：

Herr, A ^{[1
]}

Rehmert, G ^{[1
]}

Kunde, K ^{[1
]}

Gust, R ^{[1
]}

Gries, A ^{[1
]}

机构：

[1] Univ Heidelberg, Klin Anaesthesiol, D-69120 Heidelberg, Germany

来源：

ANAESTHESIST | 2002年 / 51卷 / 07期

关键词：

ARDS; anabolic steroids; body building; sepsis; Streptococcus viridans;

D O I：

10.1007/s00101-002-0335-4

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We report the case of a 30-year-old body builder who developed a gluteal abscess at the site of injection of regularly self-administered anabolic steroids. After breaking the abscess under general anaesthesia, the patient developed septic shock and fulminant adult respiratory distress syndrome (ARDS). In addition to discussing the pathogenesis, differential diagnosis, and treatment, we focus on the immunomodulatory mechanisms of anabolic substances that may have contributed to the course of the disease in this particular patient.

引用

页码：557 / 563

页数：7

共 36 条

[1] INFECTION WITH STREPTOCOCCUS-MILLERI [J].

ADMON, D ;

EPHROS, MA ;

GAVISH, D ;

RAZ, R .

JOURNAL OF INFECTION, 1987, 14 (01) :55-60

[2] Testosterone: the culprit for producing splenocyte immune depression after trauma hemorrhage [J].

Angele, MK ;

Ayala, A ;

Cioffi, WG ;

Bland, KI ;

Chaudry, IH .

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 1998, 274 (06) :C1530-C1536

[3] Effect of gender and sex hormones on immune responses following shock [J].

Angele, MK ;

Schwacha, MG ;

Ayala, A ;

Chaudry, IH .

SHOCK, 2000, 14 (02) :81-90

[4] Corticosteroids for septic shock [J].

Annane, D .

CRITICAL CARE MEDICINE, 2001, 29 (07) :S117-S120

[5] THE AMERICAN-EUROPEAN CONSENSUS CONFERENCE ON ARDS - DEFINITIONS, MECHANISMS, RELEVANT OUTCOMES, AND CLINICAL-TRIAL COORDINATION [J].

BERNARD, GR ;

ARTIGAS, A ;

BRIGHAM, KL ;

CARLET, J ;

FALKE, K ;

HUDSON, L ;

LAMY, M ;

LEGALL, JR ;

MORRIS, A ;

SPRAGG, R ;

COCHIN, B ;

LANKEN, PN ;

LEEPER, KV ;

MARINI, J ;

MURRAY, JF ;

OPPENHEIMER, L ;

PESENTI, A ;

REID, L ;

RINALDO, J ;

VILLAR, J ;

VANASBECK, BS ;

DHAINAUT, JF ;

MANCEBO, J ;

MATTHAY, M ;

MEYRICK, B ;

PAYEN, D ;

PERRET, C ;

FOWLER, AA ;

SCHALLER, MD ;

HUDSON, LD ;

HYERS, T ;

KNAUS, W ;

MATTHAY, R ;

PINSKY, M ;

BONE, RC ;

BOSKEN, C ;

JOHANSON, WG ;

LEWANDOWSKI, K ;

REPINE, J ;

RODRIGUEZROISIN, R ;

ROUSSOS, C ;

ANTONELLI, MA ;

BELOUCIF, S ;

BIHARI, D ;

BURCHARDI, H ;

LEMAIRE, F ;

MONTRAVERS, P ;

PETTY, TL ;

ROBOTHAM, J ;

ZAPOL, W .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1994, 149 (03) :818-824

[6] Clinical significance of bacteremia involving the "Streptococcus milleri" group:: 51 cases and review [J].

Bert, F ;

Bariou-Lancelin, M ;

Lambert-Zechovsky, N .

CLINICAL INFECTIOUS DISEASES, 1998, 27 (02) :385-387

[7] Steroids and steroid-like compounds [J].

Blue, JG ;

Lombardo, JA .

CLINICS IN SPORTS MEDICINE, 1999, 18 (03) :667-+

[8] TOWARD AN EPIDEMIOLOGY AND NATURAL-HISTORY OF SIRS (SYSTEMIC INFLAMMATORY RESPONSE SYNDROME) [J].

BONE, RC .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1992, 268 (24) :3452-3455

[9]

CALABRESE LH, 1989, MED SCI SPORT EXER, V21, P386

[10]

Donahue J L, 2000, Am J Ther, V7, P365, DOI 10.1097/00045391-200007060-00005

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