Developing safe therapies from human pluripotent stem cells

被引：89

作者：

Carpenter, Melissa K. ^{[1
]}

Frey-Vasconcells, Joyce ^{[2
]}

Rao, Mahendra S. ^{[3
]}

机构：

[1] Carpenter Grp, San Diego, CA USA

[2] Pharmanet Consulting, Princeton, NJ USA

[3] Invitrogen Corp, Frederick, MD USA

来源：

NATURE BIOTECHNOLOGY | 2009年 / 27卷 / 07期

关键词：

PARKINSONS-DISEASE; GENE-EXPRESSION; HUMAN ES; LINES; TRANSPLANTATION; GENERATION; SURVIVAL; DIFFERENTIATION; TUMORS; INACTIVATION;

D O I：

10.1038/nbt0709-606

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Translation of human pluripotent stem cells into cell therapies will require the development of standardized tests for product consistency, stability, tumorigenicity, toxicity and immunogenicity.

引用

页码：606 / 613

页数：8

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