Synthesis and aqueous solution characterization of catalytically active homopolymers, block copolymers and networks containing imidazole

被引：29

作者：

Patrickios, CS ^{[1
]}

Simmons, MR ^{[1
]}

机构：

[1] Univ Manchester, Inst Sci & Technol, Dept Chem Engn, Manchester M60 1QD, Lancs, England

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2000年 / 167卷 / 1-2期

基金：

英国生物技术与生命科学研究理事会; 英国惠康基金;

关键词：

group transfer polymerization; 2-(1-imidazolyl)ethyl methacrylate; 2-(dimethylamino)ethyl methacrylate; homopolymers; block copolymers; networks; catalysis; hydrolysis; enzyme mimics; micellization; water-soluble polymers; weak polyelectrolytes; 4-nitrophenyl acetate;

D O I：

10.1016/S0927-7757(99)00483-5

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Imidazole-containing polymers were prepared and characterized in terms of their hydrolytic activity. Unlike similar materials synthesized in the 1960s, the polymers are of precise molecular weight and controlled structure (random or block) afforded by the group transfer polymerization (GTP) chemistry used in the synthetic procedure. The size and composition of the copolymers were determined by gel permeation chromatography (GPC) and proton nuclear magnetic resonance spectroscopy, respectively. Aqueous solutions of the polymers were evaluated in terms of their ability to hydrolyze 4-nitrophenyl acetate. The effects of pH, polymer concentration, substrate concentration, polymer size. and structure were investigated and discussed with reference to the nucleophilicity of imidazole and the self-assembly of the block copolymers into micelles. A series of model networks based on imidazole homopolymers were also prepared and characterized in terms of their aqueous degree of swelling. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：61 / 72

页数：12

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