Grabbing Plk1 by the PBD

被引:7
作者
Dai, Wei [1 ]
Wang, Xiaoxing [1 ]
机构
[1] NYU, Sch Med, Dept Environm Med, Tuxedo Pk, NY 10987 USA
关键词
D O I
10.1016/j.molcel.2006.11.004
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A new centromeric protein termed PBIP1 was identified that recruits PIk1 to the kinetochores. In the November 3 issue of Molecular Cell, Kang et al. (2006) show that PIk1 phosphorylates PBIP1 on threonine 78, creating its own high-affinity docking site for the polo-box domain (PBD).
引用
收藏
页码:489 / 490
页数:2
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