Black cohosh and other herbal remedies associated with acute hepatitis

被引:102
作者
Whiting, PW
Clouston, A
Kerlin, P
机构
[1] Princess Alexandra Hosp, Dept Gastroenterol & Hepatol, Woolloongabba, Qld 4102, Australia
[2] Princess Alexandra Hosp, Dept Anat Pathol, Woolloongabba, Qld 4102, Australia
关键词
D O I
10.5694/j.1326-5377.2002.tb04886.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Six patients presented with clinical, biochemical and histological evidence of severe hepatitis after taking herbal remedies. One patient required urgent liver transplantation for fulminant hepatic failure after the brief use of black cohosh. Five patients took a combination of herbs and presented with jaundice, fatigue and pruritus. Healthcare providers and members of the public should be aware of the potential adverse effects of these remedies.
引用
收藏
页码:440 / 443
页数:4
相关论文
共 30 条
[1]   Pennyroyal toxicity: Measurement of toxic metabolite levels in two cases and review of the literature [J].
Anderson, IB ;
Mullen, WH ;
Meeker, JE ;
KhojastehBakht, SC ;
Oishi, S ;
Nelson, SD ;
Blanc, PD .
ANNALS OF INTERNAL MEDICINE, 1996, 124 (08) :726-+
[2]   Acute hepatitis induced by greater celandine (Chelidonium majus) [J].
Benninger, J ;
Schneider, HT ;
Schuppan, D ;
Kirchner, T ;
Hahn, EG .
GASTROENTEROLOGY, 1999, 117 (05) :1234-1237
[3]   Complementary medicine - where lies its appeal? [J].
Bensoussan, A .
MEDICAL JOURNAL OF AUSTRALIA, 1999, 170 (06) :247-248
[4]   HEPATITIS AFTER CHRONIC ABUSE OF SENNA [J].
BEUERS, U ;
SPENGLER, U ;
PAPE, GR .
LANCET, 1991, 337 (8737) :372-373
[5]   Herbal hepatotoxicity: An expanding but poorly defined problem [J].
Chitturi, S ;
Farrell, GC .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2000, 15 (10) :1093-1099
[6]  
DARCY PF, 1991, ADVERSE DRUG REACT T, V10, P189
[7]  
Duke, 1985, HDB MEDICINAL HERBS
[8]   Perceptions about complementary therapies relative to conventional therapies among adults who use both: Results from a national survey [J].
Eisenberg, DM ;
Kessler, RC ;
Van Rompay, MI ;
Kaptchuk, TJ ;
Wilkey, SA ;
Appel, S ;
Davis, RB .
ANNALS OF INTERNAL MEDICINE, 2001, 135 (05) :344-351
[9]   Harmless herbs? A review of the recent literature [J].
Ernst, E .
AMERICAN JOURNAL OF MEDICINE, 1998, 104 (02) :170-178
[10]   HEPATOTOXICITY DUE TO ATRACTYLIS-GUMMIFERA-L [J].
GEORGIOU, M ;
SIANIDOU, L ;
HATZIS, T ;
PAPADATOS, J ;
KOUTSELINIS, A .
JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY, 1988, 26 (07) :487-493