Nanoscale assembly of amine-functionalized colloidal iron oxide

被引：69

作者：

Barick, K. C. ^{[2
]}

Aslam, M. ^{[3
,6
]}

Prasad, Pottumarthi V. ^{[4
]}

Dravid, Vinayak P. ^{[1
,5
]}

Bahadur, Dhirendra ^{[2
,6
]}

机构：

[1] Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA

[2] Indian Inst Technol, Dept Met Engn & Mat Sci, Bombay 400076, Maharashtra, India

[3] Indian Inst Technol, Dept Phys, Bombay 400076, Maharashtra, India

[4] Evanston NW Healthcare, Dept Radiol, Evanston, IL 60201 USA

[5] Northwestern Univ, Int Inst Nanotechnol, Evanston, IL 60208 USA

[6] Indian Inst Technol, Ctr Res Nanotechnol & Sci, Bombay 400076, Maharashtra, India

来源：

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS | 2009年 / 321卷 / 10期

关键词：

Nanoparticle; Nanoassembly; MR contrast agent; Surface functionalization; Iron oxide; MAGNETIC NANOPARTICLES; CONTRAST AGENTS; MRI; SPHERES;

D O I：

10.1016/j.jmmm.2009.02.080

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We demonstrate a single-step facile approach for highly water-stable assembly of amine-functionalized Fe3O4 nanoparticles using thermal decomposition of Fe-chloride precursors in ethylene glycol medium in the presence of ethylenediamine. The average size of nanoassemblies is 40 perpendicular to 1 nm, wherein the individual nanoparticles are about 6nm. Amine-functionalized properties are evident from Fourier transform infrared spectrometer (FTIR), thermal and elemental analyses. The saturation magnetization and spin-echo r(2) of the nanoassemblies were measured to be 64.3emu/g and 314.6 mM(-1) s(-1), respectively. The higher value of relaxivity ratio(r(2)/r(1) = 143) indicates that nanoassemblies are a promising high-efficiency T2 contrast agent platform. & 2009 Elsevier B.V. All rights reserved.

引用

页码：1529 / 1532

页数：4

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