GLP-1 analogues: a new therapeutic approach to prevent ductopenia in cholangiopathies?

被引：6

作者：

Beuers, Ulrich ^{[1
]}

Goeke, Burkhard ^{[2
]}

机构：

[1] Univ Amsterdam, Dept Gastroenterol & Hepatol, Acad Med Ctr, NL-1100 DE Amsterdam, Netherlands

[2] Univ Munich, Dept Med 2, Klinikum Grosshadern, D-80539 Munich, Germany

来源：

GUT | 2009年 / 58卷 / 07期

关键词：

TAUROURSODEOXYCHOLIC ACID; URSODEOXYCHOLIC ACID; BILE-DUCTS; CHOLESTASIS; LIVER; EXENDIN-4; MECHANISM; SURVIVAL; RECEPTOR; AGONIST;

D O I：

10.1136/gut.2008.165688

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

引用

页码：902 / 903

页数：4

共 14 条

[1]

Proliferating cholangiocytes: A neuroendocrine compartment in the diseased liver [J].

Alvaro, Domenico ;

Mancino, Maria Grazia ;

Glaser, Shannon ;

Gaudio, Eugenio ;

Marzioni, Marco ;

Francis, Heather ;

Alpini, Gianfranco .

GASTROENTEROLOGY, 2007, 132 (01) :415-431

[2]

Biology of incretins: GLP-1 and GIP [J].

Baggio, Laurie L. ;

Drucker, Daniel J. .

GASTROENTEROLOGY, 2007, 132 (06) :2131-2157

[3]

Bayliss WM, 1902, J PHYSIOL-LONDON, V28, P325

[4]

Drug insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis [J].

Beuers, Ulrich .

NATURE CLINICAL PRACTICE GASTROENTEROLOGY & HEPATOLOGY, 2006, 3 (06) :318-328

[5]

Crosstalk of Liver, Bile Ducts and the Gut [J].

Beuers, Ulrich .

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2009, 36 (01) :1-3

[6]

GOKE R, 1993, J BIOL CHEM, V268, P19650

[7]

The cholangiopathies: Disorders of biliary epithelia [J].

Lazaridis, KN ;

Strazzabosco, M ;

Larusso, NF .

GASTROENTEROLOGY, 2004, 127 (05) :1565-1577

[8]

Ca2+-dependent cytoprotective effects of ursodeoxycholic and tauroursodeoxycholic acid on the biliary epithelium in a rat model of cholestasis and loss of bile ducts [J].

Marzioni, M ;

Francis, H ;

Benedetti, A ;

Ueno, Y ;

Fava, G ;

Venter, J ;

Reichenbach, R ;

Mancino, MG ;

Summers, R ;

Alpini, G ;

Glaser, S .

AMERICAN JOURNAL OF PATHOLOGY, 2006, 168 (02) :398-409

[9]

Exendin-4, a glucagon-like peptide 1 receptor agonist, protects cholangiocytes from apoptosis [J].

Marzioni, M. ;

Alpini, G. ;

Saccomanno, S. ;

Candelaresi, C. ;

Venter, J. ;

Rychlicki, C. ;

Fava, G. ;

Francis, H. ;

Trozzi, L. ;

Benedetti, A. .

GUT, 2009, 58 (07) :990-997

[10]

Glucagon-like peptide-1 and its receptor agonist exendin-4 modulate cholangiocyte adaptive response to cholestasis [J].

Marzioni, Marco ;

Alpini, Gianfranco ;

Saccomanno, Stefania ;

Candelaresi, Cinzia ;

Venter, Juliet ;

Rychlicki, Chiara ;

Fava, Giammarco ;

Francis, Heather ;

Trozzi, Luciano ;

Glaser, Shannon ;

Benedetti, Antonio .

GASTROENTEROLOGY, 2007, 133 (01) :244-255

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