Cardiovascular effects after low-dose exposure and radiotherapy: what research is needed?

被引:4
作者
Wondergem, Jan [1 ]
Boerma, Marjan [2 ]
Kodama, Kazunori [3 ]
Stewart, Fiona A. [4 ]
Trott, Klaus R.
机构
[1] IAEA, Dept Nucl Sci & Applicat, Div Human Hlth, Appl Radiat Biol & Radiotherapy Sect, A-1400 Vienna, Austria
[2] Univ Arkansas Med Sci, Div Radiat Hlth, Dept Pharmaceut Sci, Little Rock, AR 72205 USA
[3] Radiat Effects Res Fdn, Minami Ku, Hiroshima 7320815, Japan
[4] Netherlands Canc Inst, Biol Stress Response H3, NL-1066 CX Amsterdam, Netherlands
关键词
Radiotherapy; Breast cancer; Heart; Cardiovascular effects; Radiation-induced heart diseases; Ionising radiation; A-bomb survivors; IAEA; INDUCED HEART-DISEASE; BREAST-CANCER RADIOTHERAPY; IONIZING-RADIATION; MEDIASTINAL RADIOTHERAPY; CIRCULATORY DISEASE; MORTALITY; SURVIVORS; IRRADIATION; RISK; DAMAGE;
D O I
10.1007/s00411-013-0489-2
中图分类号
Q [生物科学];
学科分类号
090105 [作物生产系统与生态工程];
摘要
The authors of this report met at the Head Quarter of the International Atomic Energy Agency (IAEA) in Vienna, Austria, on 2-4 July 2012, for intensive discussions of an abundance of original publications on new epidemiological studies on cardiovascular effects after low-dose exposure and radiotherapy and radiobiological experiments as well as several comprehensive reviews that were published since the previous meeting by experts sponsored by the IAEA in June 2006. The data necessitated a re-evaluation of the situation with special emphasis on the consequences current experimental and clinical data may have for clinical oncology/radiotherapy and radiobiological research. The authors jointly arrived at the conclusions and recommendations presented here.
引用
收藏
页码:425 / 434
页数:10
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