Translational repression: A duet of Nanos and Pumilio

被引:82
作者
Parisi, M [1 ]
Lin, HF [1 ]
机构
[1] Duke Univ, Med Ctr, Dept Cell Biol, Durham, NC 27710 USA
关键词
D O I
10.1016/S0960-9822(00)00283-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Recent studies have shed new light on translational repression by Nanos and Pumilio proteins. The ancestral function of this repression mechanism appears to be in early germline development; later, species-specific applications in embryonic patterning and spermatogenesis-oogenesis switching evolved.
引用
收藏
页码:R81 / R83
页数:3
相关论文
共 16 条
[1]  
Arrizabalaga G, 1999, GENETICS, V153, P1825
[2]   Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos [J].
Asaoka-Taguchi, M ;
Yamada, M ;
Nakamura, A ;
Hanyu, K ;
Kobayashi, S .
NATURE CELL BIOLOGY, 1999, 1 (07) :431-437
[3]   Novel functions of nanos in downregulating mitosis and transcription during the development of the Drosophila germline [J].
Deshpande, G ;
Calhoun, G ;
Yanowitz, JL ;
Schedl, PD .
CELL, 1999, 99 (03) :271-281
[4]  
Forbes A, 1998, DEVELOPMENT, V125, P679
[5]   Essential role of the posterior morphogen nanos for germline development in Drosophila [J].
Kobayashi, S ;
Yamada, M ;
Asaoka, M ;
Kitamura, T .
NATURE, 1996, 380 (6576) :708-711
[6]   NANOS-3 and FBF proteins physically interact to control the sperm-oocyte switch in Caenorhabditis elegans [J].
Kraemer, B ;
Crittenden, S ;
Gallegos, M ;
Moulder, G ;
Barstead, R ;
Kimble, J ;
Wickens, M .
CURRENT BIOLOGY, 1999, 9 (18) :1009-1018
[7]  
Lin HF, 1997, DEVELOPMENT, V124, P2463
[8]  
MACDONALD PM, 1992, DEVELOPMENT, V114, P221
[9]   BINDING OF PUMILIO TO MATERNAL HUNCHBACK MESSENGER-RNA IS REQUIRED FOR POSTERIOR PATTERNING IN DROSOPHILA EMBRYOS [J].
MURATA, Y ;
WHARTON, RP .
CELL, 1995, 80 (05) :747-756
[10]  
Parisi M, 1999, GENETICS, V153, P235