An invasive catheter flow sensor with on-chip CMOS readout electronics for the on-line determination of blood flow

被引:19
作者
Kersjes, R [1 ]
Lienscher, F [1 ]
Spiegel, E [1 ]
Manoli, Y [1 ]
Mokwa, W [1 ]
机构
[1] STERIMED GMBH,SENSOR DEPT,D-48165 MUNSTER,GERMANY
关键词
silicon sensors; blood bow; on-chip electronics; catheters; silicon membranes; invasive measurement;
D O I
10.1016/S0924-4247(97)80015-5
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
A silicon flow sensor with integrated electronics for invasive blood-flow measurement has been developed and investigated. The flow sensor is based on a silicon-on-insulator SIMOX (separation by implanted oxygen) substrate with a backside etched silicon membrane containing oxide trenches and uses a differential thermal measurement principle. The chosen fabrication process is fully CMOS-compatible. An on-chip switched-capacitor circuitry converts the Row signal into a pulse-width-modulated signal. The device has been tested in a blood-circulation simulator in the flow range 0-101 min(-1) within a vessel with a diameter of 2 cm. It has been found to be useful for the observation of time-dependent flow pulses as well as for the determination of the cardiac output. A prototype version of the Bow-sensor system has a membrane temperature of less than 2 K above ambient temperature, a total power consumption of 5 mW and shows a pulse-width change from 45 to 25 mu s for the flow range 0-101 min-(1).
引用
收藏
页码:563 / 567
页数:5
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