Gene amplification: Yeast takes a turn

被引：30

作者：

Haber, James E. ^{[1
]}

Debatisse, Michelle

机构：

[1] Brandeis Univ, Rosenstiel Ctr, Waltham, MA 02254 USA

[2] Brandeis Univ, Dept Biol, Waltham, MA 02254 USA

[3] Univ Paris 06, Inst Curie, CNRS, UMR 7147,Sect Rech, F-75248 Paris 05, France

来源：

CELL | 2006年 / 125卷 / 07期

关键词：

D O I：

10.1016/j.cell.2006.06.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The origins of gene amplifications in mammalian cells has been difficult to analyze because of secondary genome arrangements. Recent studies in budding yeast, including Narayanan et al. (2006) in this issue of Cell, have provided new insights in the role of palindromic sequences in gene amplification.

引用

页码：1237 / 1240

页数：4

共 20 条

[1] Cycles of chromosome instability are associated with a fragile site and are increased by defects in DNA replication and checkpoint controls in yeast [J].

Admire, A ;

Shanks, L ;

Danzl, N ;

Wang, M ;

Weier, U ;

Stevens, W ;

Hunt, E ;

Weinert, T .

GENES & DEVELOPMENT, 2006, 20 (02) :159-173

[2] Induction of large DNA palindrome formation in yeast: Implications for gene amplification and genome stability in eukaryotes [J].

Butler, DK ;

Yasuda, LE ;

Yao, MC .

CELL, 1996, 87 (06) :1115-1122

[3]

Debatisse M, 1998, RECENT RES CANCER, V154, P216

[4] Mechanisms of common fragile site instability [J].

Glover, TW ;

Arlt, MF ;

Casper, AM ;

Durkin, SG .

HUMAN MOLECULAR GENETICS, 2005, 14 :R197-R205

[5] Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments [J].

Koszul, R ;

Caburet, S ;

Dujon, B ;

Fischer, G .

EMBO JOURNAL, 2004, 23 (01) :234-243

[6] Chromosomal translocations in yeast induced by low levels of DNA polymerase: A model for chromosome fragile sites [J].

Lemoine, FJ ;

Degtyareva, NP ;

Lobachev, K ;

Petes, TD .

CELL, 2005, 120 (05) :587-598

[7] The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements [J].

Lobachev, KS ;

Gordenin, DA ;

Resnick, MA .

CELL, 2002, 108 (02) :183-193

[8] RAD51-independent break-induced replication to repair a broken chromosome depends on a distant enhancer site [J].

Malkova, A ;

Signon, L ;

Schaefer, CB ;

Naylor, ML ;

Theis, JF ;

Newlon, CS ;

Haber, JE .

GENES & DEVELOPMENT, 2001, 15 (09) :1055-1060

[9] Telomerase- and recombination-independent immortalization of budding yeast [J].

Maringele, L ;

Lydall, D .

GENES & DEVELOPMENT, 2004, 18 (21) :2663-2675

[10] Break-induced replication and recombinational telomere elongation in yeast [J].

McEachern, Michael J. ;

Haber, James E. .

ANNUAL REVIEW OF BIOCHEMISTRY, 2006, 75 :111-135

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