An enantioselective indium-mediated allylation reaction of aldehydes and ketones in dichloromethane

被引：60

作者：

Loh, TP ^{[1
]}

Zhou, JR ^{[1
]}

Li, XR ^{[1
]}

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 119260, Singapore

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 52期

关键词：

enantioselectivity; indium; allylation; carbonyl; trifluoromethyl;

D O I：

10.1016/S0040-4039(99)01976-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An enantioselective indium-mediated addition reaction of allylic bromides to carbonyl compounds was achieved in dichloromethane in the presence of (-)-cinchonidine. The desired products were obtained in moderate to excellent yields and with up to 75% enantioselectivity. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9333 / 9336

页数：4

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