Refractive-index detection by interferometric backscatter in packed-capillary high-performance liquid chromatography

被引：21

作者：

Kenmore, CK

Erskine, SR

Bornhop, DJ

机构：

[1] TEXAS TECH UNIV,DEPT CHEM & BIOCHEM,LUBBOCK,TX 79409

[2] DOW CHEM CO USA,ANALYT & ENGN SCI,FREEPORT,TX 77541

来源：

JOURNAL OF CHROMATOGRAPHY A | 1997年 / 762卷 / 1-2期

关键词：

refractive index detection; detection; LC; interferometric backscatter; aromatic compounds; sodium chloride;

D O I：

10.1016/S0021-9673(96)00852-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple, inexpensive, micro-volume refractive index detector has been applied to packed capillary high-performance liquid chromatography, Nanoliter detector volumes produced by a unique optical train, based on interferometric backscatter, allows for universal solute detection at the picogram level. System utility is demonstrated by reversed-phase separation of a test mixture containing ppm levels of NaCl, phenol, ethyl benzene and toluene.

引用

页码：219 / 225

页数：7

共 31 条

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Andrews D. L., 1990, LASERS CHEM

[2]

Born M., 1975, PRINCIPLES OPTICS

[3] SUBNANOLITER LASER-BASED REFRACTIVE-INDEX DETECTOR FOR 0.25-MM ID MICROBORE LIQUID-CHROMATOGRAPHY - REVERSED-PHASE SEPARATION OF NANOGRAM AMOUNTS OF SUGARS [J].