10 Questions About 4-Aminopyridine and the Treatment of Multiple Sclerosis

被引：1

作者：

Bever, Christopher T., Jr. ^{[1
,2
]}

机构：

[1] Univ Maryland, Sch Med, UMH, Dept Neurol, Baltimore, MD 21201 USA

[2] VA Multiple Selerosis Ctr Excellence E, VA Maryland Healthcare Syst, Res & Neurol Serv, Baltimore, MD USA

来源：

NEUROLOGIST | 2009年 / 15卷 / 03期

关键词：

MAMMALIAN NERVE-FIBERS; DOUBLE-BLIND; SYMPTOMATIC TREATMENT; CLINICAL SIGNS;

D O I：

10.1097/NRL.0b013e3181679be5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

引用

页码：161 / 162

页数：2

共 23 条

[1] THE EFFECTS OF 4-AMINOPYRIDINE IN MULTIPLE-SCLEROSIS PATIENTS - RESULTS OF A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, CONCENTRATION-CONTROLLED, CROSSOVER TRIAL [J].

BEVER, CT ;

YOUNG, D ;

ANDERSON, PA ;

KRUMHOLZ, A ;

CONWAY, K ;

LESLIE, J ;

EDDINGTON, N ;

PLAISANCE, KI ;

PANITCH, HS ;

DHIBJALBUT, S ;

FOSSLER, MJ ;

DEVANE, J ;

JOHNSON, KP .

NEUROLOGY, 1994, 44 (06) :1054-1059

[2] THE EFFECTS OF 4-AMINOPYRIDINE AND TETRAETHYLAMMONIUM IONS ON NORMAL AND DEMYELINATED MAMMALIAN NERVE-FIBERS [J].

BOSTOCK, H ;

SEARS, TA ;

SHERRATT, RM .

JOURNAL OF PHYSIOLOGY-LONDON, 1981, 313 (APR) :301-315

[3] ORALLY-ADMINISTERED 4-AMINOPYRIDINE IMPROVES CLINICAL SIGNS IN MULTIPLE-SCLEROSIS [J].

DAVIS, FA ;

STEFOSKI, D ;

RUSH, J .

ANNALS OF NEUROLOGY, 1990, 27 (02) :186-192

[4]

DEGRAZIO JW, 1971, J WILDLIFE MANAGE, V35, P565, DOI 10.2307/3799716

[5] THE USE OF POTASSIUM CHANNEL BLOCKING-AGENTS IN THE THERAPY OF DEMYELINATING DISEASES [J].

FELTS, PA ;

SMITH, KJ .

ANNALS OF NEUROLOGY, 1994, 36 (03) :454-454

[6] The effects of 4-aminopyridine on motor evoked potentials in multiple sclerosis [J].

Fujihara, K ;

Miyoshi, T .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1998, 159 (01) :102-106

[7] Fampridine-SR in multiple sclerosis: a randomized, double-blind, placebo-controlled, dose-ranging study [J].

Goodman, A. D. ;

Cohen, J. A. ;

Cross, A. ;

Vollmer, T. ;

Rizzo, M. ;

Cohen, R. ;

Marinucci, L. ;

Blight, A. R. .

MULTIPLE SCLEROSIS, 2007, 13 (03) :357-368

[8] EFFECTS OF 4-AMINOPYRIDINE IN PATIENTS WITH MULTIPLE-SCLEROSIS [J].

JONES, RE ;

HERON, JR ;

FOSTER, DH ;

SNELGAR, RS ;

MASON, RJ .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1983, 60 (03) :353-362

[9] Potassium channel blockers in multiple sclerosis:: Neuronal KV channels and effects of symptomatic treatment [J].

Judge, Susan I. V. ;

Bever, Christopher T., Jr. .

PHARMACOLOGY & THERAPEUTICS, 2006, 111 (01) :224-259

[10] DIFFERENT EFFECTS OF 4-AMINOPYRIDINE ON SENSORY AND MOTOR FIBERS - PATHOGENESIS OF PARESTHESIAS [J].

KOCSIS, JD ;

BOWE, CM ;

WAXMAN, SG .

NEUROLOGY, 1986, 36 (01) :117-120

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