Capillary electrophoretic determination of sanguinarine and chelerythrine in plant extracts and pharmaceutical preparations

被引：31

作者：

Sevcík, J

Vicar, J

Ulrichová, J

Válka, I

Lemr, K

Simánek, V

机构：

[1] Palacky Univ, Lab Bioanalyt Res, Olomouc 77126, Czech Republic

[2] Palacky Univ, Dept Analyt Chem, Olomouc 77146, Czech Republic

[3] Palacky Univ, Inst Med Chem & Biochem, Olomouc 77515, Czech Republic

来源：

JOURNAL OF CHROMATOGRAPHY A | 2000年 / 866卷 / 02期

关键词：

plant materials; pharmaceutical analysis; sanguinarine; chelerythrine; alkaloids;

D O I：

10.1016/S0021-9673(99)01126-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Capillary electrophoresis was employed to determine the principal quaternary benzo[c]phenanthridine alkaloids, sanguinarine and chelerythrine, in two plant extracts and one oral hygiene product. Phosphate-Tris buffer of pH 2.5 was used as a background electrolyte, limits of detection were 3 mu mol 1(-1) (sanguinarine) and 2.4 mu mol 1(-1) (chelerythrine) using UV detection at 270 nm. The method, which correlated well with HPLC, is suitable for serial determination of sanguinarine and chelerythrine in plant products and pharmaceuticals. (C) 2000 Published by Elsevier Science B.V. All rights reserved.

引用

页码：293 / 298

页数：6

共 19 条

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