Manipulating immune responses with immunosuppressive agents that target NFAT

被引:249
作者
Kiani, A
Rao, A [1 ]
Aramburu, J
机构
[1] Harvard Univ, Sch Med, Dept Pathol, Boston, MA 02115 USA
[2] Tech Univ Dresden, Med Klin 1, Klinikum Carl Gustav Carus, D-01307 Dresden, Germany
[3] Ctr Blood Res, Boston, MA 02115 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1016/S1074-7613(00)80188-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:359 / 372
页数:14
相关论文
共 120 条
[1]   Activation and cellular localization of the cyclosporine A-sensitive transcription factor NF-AT in skeletal muscle cells [J].
Abbott, KL ;
Friday, BB ;
Thaloor, D ;
Murphy, TJ ;
Pavlath, GK .
MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (10) :2905-2916
[2]   Selective inhibition of NFAT activation by a peptide spanning the calcineurin targeting site of NFAT [J].
Aramburu, J ;
Garcia-Cozar, F ;
Raghavan, A ;
Okamura, H ;
Rao, A ;
Hogan, PG .
MOLECULAR CELL, 1998, 1 (05) :627-637
[3]  
Aramburu J, 2000, CURR TOP CELL REGUL, V36, P237
[4]   Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A [J].
Aramburu, J ;
Yaffe, MB ;
López-Rodríguez, C ;
Cantley, LC ;
Hogan, PG ;
Rao, A .
SCIENCE, 1999, 285 (5436) :2129-2133
[5]  
Armesilla AL, 1999, MOL CELL BIOL, V19, P2032
[6]   IMMUNOSUPPRESSION BY GLUCOCORTICOIDS - INHIBITION OF NF-KAPPA-B ACTIVITY THROUGH INDUCTION OF I-KAPPA-B SYNTHESIS [J].
AUPHAN, N ;
DIDONATO, JA ;
ROSETTE, C ;
HELMBERG, A ;
KARIN, M .
SCIENCE, 1995, 270 (5234) :286-290
[7]   Cyclosporine A up-regulates angiotensin II receptors and calcium responses in human vascular smooth muscle cells [J].
Avdonin, PV ;
Cottet-Maire, F ;
Afanasjeva, GV ;
Loktionova, SA ;
Lhote, P ;
Ruegg, UT .
KIDNEY INTERNATIONAL, 1999, 55 (06) :2407-2414
[8]   CBP/p300 integrates Raf/Rac-signaling pathways in the transcriptional induction of NF-ATc during T cell activation [J].
Avots, A ;
Buttmann, M ;
Chuvpilo, S ;
Escher, C ;
Smola, U ;
Bannister, AJ ;
Rapp, UR ;
Kouzarides, T ;
Serfling, E .
IMMUNITY, 1999, 10 (05) :515-524
[9]   Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3 [J].
Beals, CR ;
Sheridan, CM ;
Turck, CW ;
Gardner, P ;
Crabtree, GR .
SCIENCE, 1997, 275 (5308) :1930-1933
[10]   Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction [J].
Beals, CR ;
Clipstone, NA ;
Ho, SN ;
Crabtree, GR .
GENES & DEVELOPMENT, 1997, 11 (07) :824-834