Liver injury-preventive effect of tea theanine in rats

被引:8
作者
He, P [1 ]
Wada, S [1 ]
Watanabe, N [1 ]
Sugiyama, K [1 ]
机构
[1] Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, Shizuoka 4228529, Japan
关键词
green tea; theanine; liver injury; D-galactosamine; rats;
D O I
10.1111/j.1365-2621.2000.tb15951.x
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
This study was conducted to isolate the constituent, which had a preventive effect on D-galactosamlne-induced rat liver injury, from the 70% ethanol-soluble fraction of Japanese green tea. Theanine (glutamic acid gamma-ethylamide) was identified as the active compound, and the liver injury-preventive effect of theanine was dose-dependent. L-Glutamic acid gamma-ethyl ester, but not glutamine, also brought about a significantly preventive effect on liver injury when added to the diet at equimolar levels to that of 1% theanine. The results indicate that theanine is one of the effective constituents of Japanese green tea in preventing D-galactosamine-induced liver injury.
引用
收藏
页码:30 / 33
页数:4
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