Reporting bias in retrospective ascertainment of drug-induced embryopathy

被引：47

作者：

Bar-Oz, B

Moretti, ME

Mareels, G

Van Tittelboom, T

Koren, G

机构：

[1] Hosp Sick Children, Div Clin Pharmacol, Motherisk Program, Toronto, ON M5G 1X8, Canada

[2] Univ Toronto, Chair Child Hlth Res, CIBC Wood Gundy Childrens Miracle Fdn, Toronto, ON, Canada

[3] Janssen Pharmaceut, B-2340 Beerse, Belgium

来源：

LANCET | 1999年 / 354卷 / 9191期

关键词：

D O I：

10.1016/S0140-6736(99)04411-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The rate of congenital malformations after first-trimester exposure to itraconazole was four times higher when ascertained retrospectively than prospectively (13.0 vs 3.2%, p = 0.006). Reporting bias in retrospective studies should be acknowledged in interpretation of such data.

引用

页码：1700 / 1701

页数：2

共 4 条

[1] PERCEPTION OF TERATOGENIC RISK BY PREGNANT-WOMEN EXPOSED TO DRUGS AND CHEMICALS DURING THE 1ST TRIMESTER
KOREN, G
BOLOGA, M
LONG, D
FELDMAN, Y
SHEAR, NH
[J]. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1989, 160 (05) : 1190 - 1194
[2] THE PERCEPTION OF TERATOGENIC RISK OF COCAINE
KOREN, G
GLADSTONE, D
ROBESON, C
ROBIEUX, I
[J]. TERATOLOGY, 1992, 46 (06) : 567 - 571
[3] Drug therapy - Drugs in pregnancy
Koren, G
Pastuszak, A
Ito, S
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (16) : 1128 - 1137
[4] EVALUATION AND COUNSELING OF TERATOGENIC RISK - THE MOTHERISK APPROACH
KOREN, G
GRAHAM, K
FEIGENBAUM, A
EINARSON, T
[J]. JOURNAL OF CLINICAL PHARMACOLOGY, 1993, 33 (05) : 405 - 411

← 1 →