Dissociation of different conformations of ubiquitin ions

被引：46

作者：

Badman, ER ^{[1
]}

Hoaglund-Hyzer, CS ^{[1
]}

Clemmer, DE ^{[1
]}

机构：

[1] Indiana Univ, Dept Chem, Bloomington, IN 47405 USA

来源：

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY | 2002年 / 13卷 / 06期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S1044-0305(02)00374-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The fragmentation pathways of different conformations of three charge states of ubiquitin ions are examined using ion mobility/collisional activation/time-of-flight techniques. Mass spectra for fragments for different conformers of a single charge state appear to be identical (within the experimental reproducibility). These results are consistent with a mechanism in which different conformers of each charge state rearrange to similar dissociation transition states prior to fragment formation. (C) 2002 American Society for Mass Spectrometry.

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页码：719 / 723

页数：5

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