Sleep Dysfunction and its Management in Parkinson's Disease

被引:12
作者
Kutscher, Scott J. [1 ]
Farshidpanah, Siavash [1 ]
Claassen, Daniel O. [1 ]
机构
[1] Vanderbilt Univ, Dept Neurol, Med Ctr, Nashville, TN 37232 USA
关键词
Insomnia; Excessive daytime sleepiness (EDS); Sleep fragmentation; Circadian rhythm disorders; Restless legs syndrome (RLS); Periodic limb movements in sleep (PLMS); REM behavior disorder (RBD); Obstructive sleep apnea (OSA); RESTLESS LEGS SYNDROME; DEEP BRAIN-STIMULATION; POST-HOC ANALYSIS; DAYTIME SLEEPINESS; DOUBLE-BLIND; BEHAVIOR DISORDER; DOPAMINERGIC MEDICATIONS; RETROSPECTIVE ANALYSIS; SUBTHALAMIC NUCLEUS; LIGHT THERAPY;
D O I
10.1007/s11940-014-0304-7
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
Sleep disorders are among the most common non-motor symptoms in Parkinson's Disease (PD). In some cases, symptoms can precede a diagnosis of PD by many years, but otherwise they are commonly encountered during the clinical care of patients. Unfortunately, sleep problems are under-recognized and subsequently inadequately addressed. In our experience, when properly addressed, physicians and patients are quickly aware of the often-debilitating nature of sleep dysfunction. This does not mean that solutions are easily attainable. Sleep in PD is held in a delicate balance, influenced by the disease process, medications, co-morbid symptoms, and a variety of other factors. For this reason, management of sleep in PD often requires an inter-disciplinary approach. Physicians should have an intimate knowledge of the many sleep problems apparent in PD, as well as appreciate the challenge presented by diverse therapeutic options that can both ameliorate and aggravate symptoms.
引用
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页数:16
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