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Molecular heterogeneity at the CYP2D gene locus in Nicaraguans: Impact of gene-flow from Europe

被引：24
作者：
Agundez, JAG
Ramirez, R
Hernandez, M
Llerena, A
Benitez, J
机构：
[1] UNIV EXTREMADURA, SCH MED, DEPT PHARMACOL, E-06071 BADAJOZ, SPAIN
[2] UNIV NACL AUTONOMA NICARAGUA, DEPT PHYSIOL SCI, LEON, NICARAGUA
来源：
PHARMACOGENETICS | 1997年 / 7卷 / 04期
关键词：
Nicaraguans; Hispanics; cytochrome P450; CYP2D; gene-flow;
D O I：
10.1097/00008571-199708000-00010
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：337 / 340
页数：4
相关论文
共 15 条
  • [1] Agundez JAG, 1996, PHARMACOGENETICS, V6, P501
  • [2] PREVALENCE OF CYP2D6 GENE DUPLICATION AND ITS REPERCUSSION ON THE OXIDATIVE PHENOTYPE IN A WHITE-POPULATION
    AGUNDEZ, JAG
    LEDESMA, MC
    LADERO, JM
    BENITEZ, J
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1995, 57 (03) : 265 - 269
  • [3] Aklillu E, 1996, J PHARMACOL EXP THER, V278, P441
  • [4] THE CYTOCHROME-P450 CYP2D6 ALLELIC VARIANT CYP2D6J AND RELATED POLYMORPHISMS IN A EUROPEAN POPULATION
    ARMSTRONG, M
    FAIRBROTHER, K
    IDLE, JR
    DALY, AK
    [J]. PHARMACOGENETICS, 1994, 4 (02): : 73 - 81
  • [5] ANALYSIS OF THE CYP2D6 GENE IN RELATION TO DEBRISOQUIN AND DESIPRAMINE HYDROXYLATION IN A SWEDISH POPULATION
    DAHL, ML
    JOHANSSON, I
    PALMERTZ, MP
    INGELMANSUNDBERG, M
    SJOQVIST, F
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1992, 51 (01) : 12 - 17
  • [6] DAHL ML, 1995, J PHARMACOL EXP THER, V274, P516
  • [7] Nomenclature for human CYP2D6 alleles
    Daly, AK
    Brockmoller, J
    Broly, F
    Eichelbaum, M
    Evans, WE
    Gonzalez, FJ
    Huang, JD
    Idle, JR
    IngelmanSundberg, M
    Ishizaki, T
    JacqzAigrain, E
    Meyer, UA
    Nebert, DW
    Steen, VM
    Wolf, CR
    Zanger, UM
    [J]. PHARMACOGENETICS, 1996, 6 (03): : 193 - 201
  • [8] HEIM MH, 1991, METHOD ENZYMOL, V206, P173
  • [9] INHERITED AMPLIFICATION OF AN ACTIVE GENE IN THE CYTOCHROME-P450 CYP2D LOCUS AS A CAUSE OF ULTRARAPID METABOLISM OF DEBRISOQUINE
    JOHANSSON, I
    LUNDQVIST, E
    BERTILSSON, L
    DAHL, ML
    SJOQVIST, F
    INGELMANSUNDBERG, M
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (24) : 11825 - 11829
  • [10] JOHANSSON I, 1994, MOL PHARMACOL, V46, P452
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