A Bayesian approach to validating STR multiplex databases for use in forensic casework

被引:5
作者
Foreman, LA
Smith, AFM
Evett, IW
机构
[1] METROPOLITAN POLICE FORENS SCI LAB,FORENS SCI SERV,LONDON SE1 7LP,ENGLAND
[2] UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED,DEPT MATH,LONDON SW7 2BZ,ENGLAND
关键词
DNA profiling; forensic identification; Bayesian inference; likelihood ratio; coancestry coefficient; probability; statistics; PCR; STR;
D O I
10.1007/s004140050079
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
A previous paper in this journal has described the conventional statistical analysis of three databases (Caucasian, Afro-Caribbean and Asians from the Indian subcontinent) where individuals are typed at six short tandem repeat (STR) loci. This paper presents a Bayesian analysis of the same data and the approach is centered on the concept of estimating coancestry coefficients from mixed databases. Posterior distributions for the three databases are presented and discussed and the consequences of implementing bootstrap estimation procedures an also shown.
引用
收藏
页码:244 / 250
页数:7
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