Levetiracetam in focal epilepsy and hepatic porphyria: A case report

被引：19

作者：

Paul, F ^{[1
]}

Meencke, HJ ^{[1
]}

机构：

[1] Evangel Krankenhaus Konigin Elisabeth Herzberge, Dept Epileptol, D-10362 Berlin, Germany

来源：

EPILEPSIA | 2004年 / 45卷 / 05期

关键词：

focal epilepsy; hereditary coproporphyria; levetiracetam;

D O I：

10.1111/j.0013-9580.2004.00204.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report a patient with focal epilepsy and latent hereditary coproporphyria who had exacerbation of clinical symptoms of porphyria under treatment with valproate and primidone and was then treated with levetiracetam without exacerbation of clinically latent porphyria.

引用

页码：559 / 560

页数：2

共 8 条

[1] SEIZURE MANAGEMENT IN ACUTE HEPATIC PORPHYRIA - RISKS OF VALPROATE AND CLONAZEPAM [J].

BONKOWSKY, HL ;

SINCLAIR, PR ;

EMERY, S ;

SINCLAIR, JF .

NEUROLOGY, 1980, 30 (06) :588-592

[2] Oxcarbazepine in focal epilepsy and hepatic porphyria: A case report [J].

Gaida-Hommernick, B ;

Rieck, K ;

Runge, U .

EPILEPSIA, 2001, 42 (06) :793-795

[3]

GRANICK S, 1966, J BIOL CHEM, V241, P1359

[4] Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: Potential implications for patients with acute porphyria [J].

Hahn, M ;

Gildemeister, OS ;

Krauss, GL ;

Pepe, JA ;

Lambrecht, RW ;

Donohue, S ;

Bonkovsky, HL .

NEUROLOGY, 1997, 49 (01) :97-106

[5]

HURLEY HJ, 1992, DERMATOLOGY, P1667

[6] SUCCESSFUL TREATMENT OF SEIZURES AND PORPHYRIA WITH GABAPENTIN [J].

KRAUSS, GL ;

SIMMONSOBRIEN, E ;

CAMPBELL, M .

NEUROLOGY, 1995, 45 (03) :594-595

[7] Pharmacokinetic profile of levetiracetam: toward ideal characteristics [J].

Patsalos, PN .

PHARMACOLOGY & THERAPEUTICS, 2000, 85 (02) :77-85

[8]

REYNOLDS NC, 1981, NEUROLOGY, V31, P480

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