Positive selection for autoimmunity

被引:12
作者
Datta, SK [1 ]
机构
[1] Northwestern Univ, Sch Med, Dept Med, Div Rheumatol, Chicago, IL 60611 USA
[2] Northwestern Univ, Sch Med, Dept Microbiol Immunol, Chicago, IL 60611 USA
关键词
D O I
10.1038/73101
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Negative selection of developing T cells in the thymus is not the only mechanism by which central tolerance to self antigens is acquired. Alternative possibilities are demonstrated in a new model of autoimmune disease (pages 298–305).
引用
收藏
页码:259 / 261
页数:3
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