A new clue at the nuclear pore: RanBP2 is an E3 enzyme for SUMO1

被引：20

作者：

Azuma, Y ^{[1
]}

Dasso, M ^{[1
]}

机构：

[1] NICHHD, Lab Gene Regulat & Dev, NIH, Bethesda, MD 20892 USA

来源：

DEVELOPMENTAL CELL | 2002年 / 2卷 / 02期

关键词：

D O I：

10.1016/S1534-5807(02)00124-7

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A recent paper in Cell shows that the large nucleoporin RanBP2 can act as an E3 enzyme for the ubiquitin-like protein SUMO1. These intriguing results raise important questions about the mechanism of SUMO1 conjugation, the relationship of SUMO1 to nuclear transport, and the regulation of RanBP2 in the pore.

引用

页码：130 / 131

页数：2

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