Clinical application of pulsed Doppler tissue imaging for assessing abnormal left ventricular relaxation

被引:417
作者
Oki, T [1 ]
Tabata, T [1 ]
Yamada, H [1 ]
Wakatsuki, T [1 ]
Shinohara, H [1 ]
Nishikado, A [1 ]
Iuchi, A [1 ]
Fukuda, N [1 ]
Ito, S [1 ]
机构
[1] ZENTSUJI NATL HOSP,INST CLIN RES,KAGAWA,JAPAN
关键词
D O I
10.1016/S0002-9149(97)00015-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Conventional assessment of left ventricular (LV) relaxation by calculating the time constant of LV pressure decay during the isovolumic diastole requires an invasive approach. Conversely, noninvasive parameters obtained by measuring isovolumic relaxation time and transmitral flow velocity often give inaccurate information. Using LV pressure curve, pulsed Doppler echocardiography, and poised Doppler tissue imaging in 38 patients with heart disease and 12 control subjects, we calculated the time constant and recorded transmitral flow velocity and motion velocities at the endocardial portions of the ventricular septum and LV posterior wall. Compared with the controls, patients exhibited a prolonged time constant, a decreased peak early diastolic velocity of the LV posterior wall, and a prolonged time interval from the second heart sound to the peak of the early diastolic wave. The time constant correlated well with the isovolumic relaxation time and various parameters calculated from the transmitral flow velocity, except in patients with elevated LV end-diastolic pressure. In all subjects, the time constant correlated negatively with the peak early diastolic velocity of the posterior wall and positively with the time from the second heart sound to the peak of the early diastolic wave. Thus, early diastolic parameters derived from the motion velocity of the LV posterior wall by pulsed Doppler tissue imaging were closely related to the time constant. This technique may allow noninvasive evaluation of abnormal LV relaxation in patients with various heart diseases. (C) 1997 by Excerpta Medica, Inc.
引用
收藏
页码:921 / 928
页数:8
相关论文
共 27 条
  • [1] ISOVOLUMIC RELAXATION PERIOD IN HYPERTROPHIC CARDIOMYOPATHY
    ALVARES, RF
    SHAVER, JA
    GAMBLE, WH
    GOODWIN, JF
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1984, 3 (01) : 71 - 81
  • [2] DEMONSTRATION OF RESTRICTIVE VENTRICULAR PHYSIOLOGY BY DOPPLER ECHOCARDIOGRAPHY
    APPLETON, CP
    HATLE, LK
    POPP, RL
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1988, 11 (04) : 757 - 768
  • [3] IMPAIRED LEFT-VENTRICULAR DIASTOLIC FILLING IN PATIENTS WITH CORONARY-ARTERY DISEASE - ASSESSMENT WITH RADIONUCLIDE ANGIOGRAPHY
    BONOW, RO
    BACHARACH, SL
    GREEN, MV
    KENT, KM
    ROSING, DR
    LIPSON, LC
    LEON, MB
    EPSTEIN, SE
    [J]. CIRCULATION, 1981, 64 (02) : 315 - 323
  • [4] ISCHEMIC CARDIOMYOPATHY
    BURCH, GE
    GILES, TD
    COLCOLOU.HL
    [J]. AMERICAN HEART JOURNAL, 1970, 79 (03) : 291 - &
  • [5] NONINVASIVE MEASUREMENT OF THE TIME CONSTANT OF LEFT-VENTRICULAR RELAXATION USING THE CONTINUOUS-WAVE DOPPLER VELOCITY PROFILE OF MITRAL REGURGITATION
    CHEN, CG
    RODRIGUEZ, L
    LEVINE, RA
    WEYMAN, AE
    THOMAS, JD
    [J]. CIRCULATION, 1992, 86 (01) : 272 - 278
  • [6] QUANTITATIVE DOPPLER TISSUE IMAGING OF THE LEFT-VENTRICULAR MYOCARDIUM - VALIDATION IN NORMAL SUBJECTS
    DONOVAN, CL
    ARMSTRONG, WF
    BACH, DS
    [J]. AMERICAN HEART JOURNAL, 1995, 130 (01) : 100 - 104
  • [7] CONGESTIVE HEART-FAILURE WITH NORMAL SYSTOLIC FUNCTION
    DOUGHERTY, AH
    NACCARELLI, GV
    GRAY, EL
    HICKS, CH
    GOLDSTEIN, RA
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1984, 54 (07) : 778 - 782
  • [8] DIASTOLIC PROPERTIES OF LEFT-VENTRICLE
    GROSSMAN, W
    MCLAURIN, LP
    [J]. ANNALS OF INTERNAL MEDICINE, 1976, 84 (03) : 316 - 326
  • [9] LEFT-VENTRICULAR RELAXATION AND FILLING PATTERN IN DIFFERENT FORMS OF LEFT-VENTRICULAR HYPERTROPHY - ECHOCARDIOGRAPHIC STUDY
    HANRATH, P
    MATHEY, DG
    SIEGERT, R
    BLEIFELD, W
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1980, 45 (01) : 15 - 23
  • [10] LEFT-VENTRICULAR FILLING DYNAMICS - INFLUENCE OF LEFT-VENTRICULAR RELAXATION AND LEFT ATRIAL PRESSURE
    ISHIDA, Y
    MEISNER, JS
    TSUJIOKA, K
    GALLO, JI
    YORAN, C
    FRATER, RWM
    YELLIN, EL
    [J]. CIRCULATION, 1986, 74 (01) : 187 - 196