Molecular structure and functional role of vascular tight junctions

被引：29

作者：

Bazzoni, G

Estrada, OMM

Dejana, E

机构：

[1] Mario Negri Inst Pharmacol Res, Lab Vasc Biol, I-20157 Milan, Italy

[2] Univ Insubria, Fac Med & Chirurg, Dipartimento Sci Clin & Biol, Varese, Italy

来源：

TRENDS IN CARDIOVASCULAR MEDICINE | 1999年 / 9卷 / 06期

关键词：

D O I：

10.1016/S1050-1738(99)00022-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Interendothelial tight junctions regulate paracellular permeability and maintain cell polarity. The assembly and remodeling of tight junctions are examined, focusing on the molecular interactions between tight junction components and their functional role in endothelial biology. The molecular structures or two subcellular organelles related to tight junctions, the intercalated disks in cardiomyocytes and the slit diaphragms in glomerular podocytes, are discussed. (Trends Cardiovasc Med 1999;9:147-152). (C) 1999, Elsevier Science Inc.

引用

页码：147 / 152

页数：6

共 52 条

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