Seasonal periodicity of serum vitamin D and parathyroid hormone, bone resorption, and fractures: the Geelong osteoporosis study

被引:147
作者
Pasco, JA
Henry, MJ
Kotowicz, MA
Sanders, KM
Seeman, E
Pasco, JR
Schneider, HG
Nicholson, GC
机构
[1] Univ Melbourne, Dept Clin & Biomed Sci, Barwon Hlth, Geelong, Vic 3220, Australia
[2] Univ Melbourne, Austin & Repatriat Med Ctr, Dept Med, Heidelberg, Vic, Australia
[3] Geelong Hosp, Dept Emergency Med, Barwon Hlth, Geelong, Vic 3220, Australia
[4] Alfred Pathol Serv, Prahran, Vic, Australia
关键词
vitamin D; parathyroid hormone; bone turnover markers; seasonality; population studies;
D O I
10.1359/JBMR.040125
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this population-based study, seasonal periodicity was seen with reduced serum vitamin D, increased serum PTH, and increased bone resorption in winter. This was associated with an increased proportion of falls resulting in fracture and an increased risk of wrist and hip fractures.
引用
收藏
页码:752 / 758
页数:7
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