Evolutionary history of Ebola virus

被引:40
作者
Li, Y. H. [1 ]
Chen, S. P. [2 ]
机构
[1] Acad Mil Med Sci, Affiliated Hosp, Ctr Hematopoiet Stem Cell Transplantat, Beijing 100071, Peoples R China
[2] Acad Mil Med Sci, Affiliated Hosp, Dept Lab Med, Beijing 100071, Peoples R China
关键词
Molecular epidemiology; FRUIT BATS; ORIGIN; DISEASE; SUDAN; HOST;
D O I
10.1017/S0950268813002215
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Since Ebola virus was discovered in 1970s, the virus has persisted in Africa and sporadic fatal outbreaks in humans and non-human primates have been reported. However, the evolutionary history of Ebola virus remains unclear. In this study, 27 Ebola virus strains with complete glycoprotein genes, including five species (Zaire, Sudan, Reston, Tai Forest, Bundibugyo), were analysed. Here, we propose a hypothesis of the evolutionary history of Ebola virus which will be helpful to investigate the molecular evolution of these viruses.
引用
收藏
页码:1138 / 1145
页数:8
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