Gastrointestinal bleeding after living-related liver transplantation

被引：27

作者：

Hirata, M ^{[1
]}

Kita, Y ^{[1
]}

Harihara, Y ^{[1
]}

Hisatomi, S ^{[1
]}

Sano, K ^{[1
]}

Mizuta, K ^{[1
]}

Yoshino, H ^{[1
]}

Sugawara, Y ^{[1
]}

Takayama, T ^{[1
]}

Kawarasaki, H ^{[1
]}

Hashizume, K ^{[1
]}

Makuuchi, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Liver Transplantat Team, Bunkyo Ku, Tokyo 1138655, Japan

来源：

DIGESTIVE DISEASES AND SCIENCES | 2002年 / 47卷 / 11期

关键词：

living-related liver transplantation; gastrointestinal bleeding; portal vein thrombosis; esophageal variceal bleeding;

D O I：

10.1023/A:1020570901035

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

We examined the prevalence of gastrointestinal bleeding in patients undergoing living-related liver transplantation (LRLT). Seventy-seven patients (37 male and 40 female) underwent LRLT at the University of Tokyo Hospital from January 1996 through December 1999. Forty-nine patients were children or adolescents and 28 patients were adults. The mean follow-up period was 21.3 +/- 12.8 months. Nine of the 77 recipients had gastrointestinal bleeding after transplantation. The incidence of posttransplant bleeding was significantly higher in adult recipients than in pediatric recipients (25% vs 4%, P < 0.05). The ratio of graft volume to standard liver volume was significantly lower in adult recipients than in pediatric recipients (41 +/- 6% vs 86 +/- 26%, P < 0.05). Portal vein thrombosis (PVT) developed after LRLT in 8 patients. Variceal bleeding subsequently occurred in all 4 adult patients with PVT but in only 1 of 4 pediatric patients. Small-for-size grafts may cause transient portal hypertension, which increases the risk of gastrointestinal bleeding.

引用

页码：2386 / 2388

页数：3

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