Use of serotonin re-uptake inhibitors as primary therapy for carotid sinus hypersensitivity

被引:7
作者
Dan, D [1 ]
Grubb, BP [1 ]
Mouhaffel, AH [1 ]
Kosinski, DJ [1 ]
机构
[1] MED COLL OHIO,DEPT MED,DIV CARDIOL,ELECTROPHYSIOL SECT,TOLEDO,OH 43699
来源
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY | 1997年 / 20卷 / 06期
关键词
carotid sinus syndrome; serotonin re-uptake inhibitors;
D O I
10.1111/j.1540-8159.1997.tb03532.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Carotid sinus syndrome (CSS) is a well-recognized cause of unexplained syncope in older patients, and may lead to significant morbidity related to trauma suffered during falls. Dual chamber pacing has been demonstrated to be efficacious in relieving symptoms due to bradycardia, but not the accompanying vasodepressor response. We report three patients with recurrent syncope due to a mixed type; of CSS, who were treated with serotonin re-uptake inhibitors (SSRIs) alone, and were symptom-free after 4-5 weeks of therapy. The patients have remained symptom-free after more than 13 months of treatment. We conclude that SSRIs may be potentially useful in the treatment of CSS, and that the central mechanisms involved in CSS may be similar to those that result in neurocardiogenic syncope.
引用
收藏
页码:1633 / 1635
页数:3
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