Amyloid β-Protein Assembly and Alzheimer Disease

被引：517

作者：

Roychaudhuri, Robin ^{[1
]}

Yang, Mingfeng ^{[1
]}

Hoshi, Minako M. ^{[2
]}

Teplow, David B. ^{[1
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Neurol, Los Angeles, CA 90095 USA

[2] Mitsubishi Kagaku Inst Life Sci, Tokyo 1948511, Japan

来源：

JOURNAL OF BIOLOGICAL CHEMISTRY | 2009年 / 284卷 / 08期

关键词：

OXIDATIVE STRESS; MITOCHONDRIAL DYSFUNCTION; PEPTIDE; NEURODEGENERATION; AGGREGATION; NEUROTOXICITY; MECHANISMS; MEMBRANE; DISTINCT; FIBRILS;

D O I：

10.1074/jbc.R800036200

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：4749 / 4753

页数：5

共 50 条

[1] Aβ ion channels.: Prospects for treating Alzheimer's disease with Aβ channel blockers [J].

Arispe, Nelson ;

Diaz, Juan C. ;

Simakova, Olga .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2007, 1768 (08) :1952-1965

[2] HYDROGEN-PEROXIDE MEDIATES AMYLOID-BETA PROTEIN TOXICITY [J].

BEHL, C ;

DAVIS, JB ;

LESLEY, R ;

SCHUBERT, D .

CELL, 1994, 77 (06) :817-827

[3] Rapid photochemical cross-linking - A new tool for studies of metastable, amyloidogenic protein assemblies [J].

Bitan, G ;

Teplow, DB .

ACCOUNTS OF CHEMICAL RESEARCH, 2004, 37 (06) :357-364

[4] The metallobiology of Alzheimer's disease [J].

Bush, AI .

TRENDS IN NEUROSCIENCES, 2003, 26 (04) :207-214

[5] Amyloid β-peptide [1-42]-associated free radical-induced oxidative stress and neurodegeneration in Alzheimer's disease grain:: Mechanisms and consequences [J].

Butterfield, DA .

CURRENT MEDICINAL CHEMISTRY, 2003, 10 (24) :2651-2659

[6] Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders [J].

Caughey, B ;

Lansbury, PT .

ANNUAL REVIEW OF NEUROSCIENCE, 2003, 26 :267-298

[7]

Chen JX, 2007, J ALZHEIMERS DIS, V12, P177

[8] Distinct early folding and aggregation properties of Alzheimer amyloid-β peptides Aβ40 and Aβ42 -: Stable trimer or tetramer formation by Aβ42 [J].

Chen, Yun-Ru ;

Glabe, Charles G. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (34) :24414-24422

[9] ERK1/2 activation mediates Aβ oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures [J].

Chong, Young Hae ;

Shin, Yoo Jeong ;

Lee, Eun Ok ;

Kayed, Rakez ;

Glabe, Charles G. ;

Tenner, Andrea J. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2006, 281 (29) :20315-20325

[10] Mitochondria in aging and Alzheimer's disease [J].

Crouch, P. J. ;

Cimdins, K. ;

Duce, J. A. ;

Bush, A. I. ;

Trounce, I. A. .

REJUVENATION RESEARCH, 2007, 10 (03) :349-357

← 1 2 3 4 5 →