The new field of 'precision psychiatry'

被引:345
作者
Fernandes, Brisa S. [1 ,2 ,3 ]
Williams, Leanne M. [4 ,5 ]
Steiner, Johann [6 ]
Leboyer, Marion [7 ]
Carvalho, Andre F. [8 ]
Berk, Michael [1 ,2 ,9 ,10 ]
机构
[1] Deakin Univ, Sch Med, Fac Hlth, IMPACT Strateg Res Ctr, Waurn Ponds, Vic 3216, Australia
[2] Barwon Hlth Univ Hosp, Geelong, Vic, Australia
[3] Univ Fed Rio Grande do Sul, Dept Biochem, Lab Calcium Binding Prot Cent Nervous Syst, Porto Alegre, RS, Brazil
[4] Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Stanford, CA USA
[5] VA Palo Alto Hlth Care Syst, MIRECC, Palo Alto, CA USA
[6] Univ Magdeburg, Dept Psychiat, Magdeburg, Germany
[7] Univ Paris Est Creteil, Dept Psychiat, AP HP, INSERM U955,Translat Psychiat,Fdn FondaMental, Creteil, France
[8] Univ Fed Ceara, Dept Clin Med, Translat Psychiat Res Grp, Fac Med, Fortaleza, Ceara, Brazil
[9] Univ Melbourne, Florey Inst Neurosci & Mental Hlth, Dept Psychiat, Melbourne, Vic, Australia
[10] Univ Melbourne, Orygen, Natl Ctr Excellence Youth Mental Hlth, Melbourne, Vic, Australia
基金
澳大利亚国家健康与医学研究理事会;
关键词
Precision medicine; Personalised medicine; Precision psychiatry; Systems biology; Biomarkers; Big data; Research domain criteria; Omics; IMPLEMENTATION SCIENCE; SYSTEMS BIOLOGY; MEDICINE; NEUROSCIENCE; BIOMARKER; BIAS;
D O I
10.1186/s12916-017-0849-x
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Background: Precision medicine is a new and important topic in psychiatry. Psychiatry has not yet benefited from the advanced diagnostic and therapeutic technologies that form an integral part of other clinical specialties. Thus, the vision of precision medicine as applied to psychiatry-'precision psychiatry' -promises to be even more transformative than in other fields of medicine, which have already lessened the translational gap. Discussion: Herein, we describe ` precision psychiatry' and how its several implications promise to transform the psychiatric landscape. We pay particular attention to biomarkers and to how the development of new technologies now makes their discovery possible and timely. The adoption of the term 'precision psychiatry' will help propel the field, since the current term 'precision medicine', as applied to psychiatry, is impractical and does not appropriately distinguish the field. Naming the field 'precision psychiatry' will help establish a stronger, unique identity to what promises to be the most important area in psychiatry in years to come. Conclusion: In summary, we provide a wide-angle lens overview of what this new field is, suggest how to propel the field forward, and provide a vision of the near future, with 'precision psychiatry' representing a paradigm shift that promises to change the landscape of how psychiatry is currently conceived.
引用
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页数:7
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