An epithermal facility for treating brain gliomas at the TAPIRO reactor

被引：3

作者：

Burn, KW

Casalini, L

Martini, S

Mazzini, W

Nava, E

Petrovich, C

Rosi, G

Sarotto, M

Tinti, R

机构：

[1] ENEA, FIS NUC, I-40129 Bologna, Italy

[2] Univ Pisa, DIMNP, I-56126 Pisa, Italy

[3] ENEA, FIS ION, I-00060 Rome, Italy

来源：

APPLIED RADIATION AND ISOTOPES | 2004年 / 61卷 / 05期

关键词：

fast reactor; epithermal column; Monte Carlo; MCNP; anthropomorphic phantom; therapeutic figures-of-merit;

D O I：

10.1016/j.apradiso.2004.05.052

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An epithermal facility for treating patients with brain gliomas has been designed and is under construction at the fast reactor TAPIRO at ENEA Casaccia (Italy). The calculational design tools employed were the Monte Carlo codes MCNP/MCNPX together with the DSA in-house variance reduction patch. A realistic anthropomorphic phantom ("ADAM") was included to optimise dose profiles and in-phantom treatment-planning figures-of-merit. The adopted approach was to minimise the treatment time whilst maintaining a reasonable therapeutic ratio. It is shown that TAPIRO, in spite of its low power of 5 kW, is able to provide an epithermal beam that is of good quality and of sufficient intensity to allow a single beam patient irradiation, under conservative assumptions, of 50 min. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：987 / 991

页数：5

共 10 条

[1]

AGOSTEO S, 2003, INT C RES REACT UT S

[2]

Briesmeister J.F, 1997, MCNP GEN MONTE CARLO

[3]

Burn KW, 2002, RESEARCH AND DEVELOPMENT IN NEUTRON CAPTURE THERAPY, P129

[4]

BURN KW, 2000, P C MONT CARL 2000 L, P687

[5] The fission converter-based epithermal neutron irradiation facility at the Massachusetts Institute of Technology reactor [J].

Harling, OK ;

Riley, KJ ;

Newton, TH ;

Wilson, BA ;

Bernard, JA ;

Hu, LW ;

Fonteneau, EJ ;

Menadier, PT ;

Ali, SJ ;

Sutharshan, B ;

Kohse, GE ;

Ostrovsky, Y ;

Stahle, PW ;

Binns, PJ ;

Kiger, WS .

NUCLEAR SCIENCE AND ENGINEERING, 2002, 140 (03) :223-240

[6]

*INT COMM RAD UN M, 1992, 46 ICRU

[7]

International Atomic Energy Agency, 2001, TECDOC 1223, P196

[8]

Kramer R, 1982, S885 GSF 1

[9]

Waters L-S, 1999, MCNPX USERS MANUAL V

[10]

ZAMENHOF RG, 2002, COMMUNICATION 0227

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