Altered cardiac myocyte Ca regulation in heart failure

被引：257

作者：

Bers, Donald M. ^{[1
]}

机构：

[1] Loyola Univ, Stritch Sch Med, Dept Physiol, Maywood, IL 60611 USA

来源：

PHYSIOLOGY | 2006年 / 21卷

关键词：

D O I：

10.1152/physiol.00019.2006

中图分类号：

Q4 [生理学];

学科分类号：

071003 [生理学];

摘要：

Ca is critical in both the electrical and mechanical properties of cardiac myocytes, and much is known about ionic currents and the normal excitation-contraction coupling process. In heart failure, there are significant alterations in how myocyte Ca is regulated, and these alterations are critical in dictating both contractile dysfunction and certain cardiac arrhythmias that are characteristic of heart failure.

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收藏

页码：380 / 387

页数：8

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