Lymphoid interstitial pneumonitis associated with common variable hypogammaglobulinaemia treated with cyclosporin A

Lymphoid interstitial pneumonitis (LIP) is a rare clinicopathological entity that may be associated with common variable immune deficiency (CVID) and may lead to respiratory failure and death. Some patients may respond to prolonged corticosteroid treatment. We hypothesised that, in view of the predominant T cell nature of LIP, cyclosporin A would be a more appropriate choice of immunosuppressive agent and report: the first case of its successful use in a woman with LIP associated with CVID.