Specific microbiome-dependent mechanisms underlie the energy harvest efficiency of ruminants

被引:765
作者
Ben Shabat, Sheerli Kruger [1 ,2 ,3 ,4 ]
Sasson, Goor [1 ,2 ]
Doron-Faigenboim, Adi [3 ]
Durman, Thomer [1 ,2 ]
Yaacoby, Shamay [3 ]
Miller, Margret E. Berg [5 ,6 ]
White, Bryan A. [5 ,6 ]
Shterzer, Naama [1 ,2 ]
Mizrahi, Itzhak [1 ,2 ]
机构
[1] Ben Gurion Univ Negev, Dept Life Sci, POB 653, IL-84105 Beer Sheva, Israel
[2] Ben Gurion Univ Negev, Natl Inst Biotechnol Negev, POB 653, IL-84105 Beer Sheva, Israel
[3] Agr Res Org, Volcani Ctr, Inst Anim Sci, Dept Ruminant Sci, Bet Dagan, Israel
[4] Tel Aviv Univ, Dept Mol Microbiol & Biotechnol, George S Wise Fac Life Sci, Ramat Aviv, Israel
[5] Univ Illinois, Dept Anim Sci, 328 Mumford Hall, Urbana, IL 61801 USA
[6] Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA
基金
欧洲研究理事会; 以色列科学基金会;
关键词
METHANE PRODUCTION; FEED-EFFICIENCY; LIVESTOCK PRODUCTION; BACTERIAL COMMUNITY; GUT MICROBIOME; BEEF-CATTLE; DAIRY-COWS; RUMEN; MONENSIN; FIBER;
D O I
10.1038/ismej.2016.62
中图分类号
Q14 [生态学(生物生态学)];
学科分类号
071301 [植物生态学];
摘要
Ruminants have the remarkable ability to convert human-indigestible plant biomass into human-digestible food products, due to a complex microbiome residing in the rumen compartment of their upper digestive tract. Here we report the discovery that rumen microbiome components are tightly linked to cows' ability to extract energy from their feed, termed feed efficiency. Feed efficiency was measured in 146 milking cows and analyses of the taxonomic composition, gene content, microbial activity and metabolomic composition was performed on the rumen microbiomes from the 78 most extreme animals. Lower richness of microbiome gene content and taxa was tightly linked to higher feed efficiency. Microbiome genes and species accurately predicted the animals' feed efficiency phenotype. Specific enrichment of microbes and metabolic pathways in each of these microbiome groups resulted in better energy and carbon channeling to the animal, while lowering methane emissions to the atmosphere. This ecological and mechanistic understanding of the rumen microbiome could lead to an increase in available food resources and environmentally friendly livestock agriculture.
引用
收藏
页码:2958 / 2972
页数:15
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