Pearls and pitfalls in the therapeutic use of botulinum toxin

被引：7

作者：

Smith, AG ^{[1
]}

机构：

[1] Univ Utah, Dept Neurol, Therapeut Botulinum Toxin Clin, Salt Lake City, UT 84132 USA

来源：

SEMINARS IN NEUROLOGY | 2004年 / 24卷 / 02期

关键词：

botulinum toxin; dystonia; therapy;

D O I：

10.1055/s-2004-830902

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Botulinum toxin is a potent toxin and powerful therapeutic tool. Botulinum toxin has therapeutic application in the treatment of a host of neurological, ophthalmologic, gastroenterological, urologic, and dermatologic conditions. Although there are issues specific to each disorder for which botulinum toxin therapy is employed, there are several common principles. This article reviews several of these general principles by addressing common questions that arise in the therapeutic use of botulinum toxin. Areas of focus include patient selection, drug preparation and delivery, use of electromyography to guide injections, drug resistance, and organization of a therapeutic botulinum toxin clinic.

引用

页码：165 / 174

页数：10

共 65 条

[1]

Aoki KR, 2003, HEADACHE, V43, pS9

[2]

Aoki KR, 2001, J NEUROL, V248, pS3

[3] Needle EMG guidance is useful [J].

Barbano, RL .

MUSCLE & NERVE, 2001, 24 (11) :1567-1568

[4] Botulinum toxin type A (BOTOX) for treatment of migraine headaches: An open-label study [J].

Binder, WJ ;

Brin, MF ;

Blitzer, A ;

Schoenrock, LD ;

Pogoda, JM .

OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2000, 123 (06) :669-676

[5] Sudomotor testing predicts the presence of neutralizing botulinum A toxin antibodies [J].

Birklein, F ;

Walther, D ;

Bigalke, H ;

Winterholler, M ;

Erbguth, F .

ANNALS OF NEUROLOGY, 2002, 52 (01) :68-73

[6]

Birklein F, 2000, MOVEMENT DISORD, V15, P146, DOI 10.1002/1531-8257(200001)15:1<146::AID-MDS1023>3.0.CO

[7]

2-X

[8]

BLUMENFELD A, 2002, HEADACHE, V42, P409

[9] HISTOLOGIC ASSESSMENT OF DOSE-RELATED DIFFUSION AND MUSCLE-FIBER RESPONSE AFTER THERAPEUTIC BOTULINUM-A TOXIN INJECTIONS [J].

BORODIC, GE ;

FERRANTE, R ;

PEARCE, LB ;

SMITH, K .

MOVEMENT DISORDERS, 1994, 9 (01) :31-39

[10] BOTULINUM TOXIN IN CERVICAL DYSTONIA - LOW-DOSAGE WITH ELECTROMYOGRAPHIC GUIDANCE [J].

BRANS, JWM ;

DEBOER, IP ;

ARAMIDEH, M ;

DEVISSER, BWO ;

SPEELMAN, JD .

JOURNAL OF NEUROLOGY, 1995, 242 (08) :529-534

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