How I treat sinusoidal obstruction syndrome

被引：47

作者：

Chao, Nelson ^{[1
]}

机构：

[1] Duke Univ, Div Hematol Malignancies & Cellular Therapy, Durham, NC 27710 USA

来源：

BLOOD | 2014年 / 123卷 / 26期

关键词：

BONE-MARROW-TRANSPLANTATION; HEPATIC VENOOCCLUSIVE DISEASE; STEM-CELL TRANSPLANTATION; C VIRUS-INFECTION; MULTISYSTEM ORGAN FAILURE; PLASMA-PROTEIN C; LIVER-DISEASE; INTRAVENOUS BUSULFAN; SIGNIFICANT TOXICITY; ENDOTHELIAL-CELLS;

D O I：

10.1182/blood-2014-03-551630

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Sinusoidal obstruction syndrome (SOS), previously called veno-occlusive disease (VOD) can be a difficult problem after hematopoietic cell transplantation (HCT). The overall incidence has changed since the early days of allogeneic HCT. Prophylaxis and treatment remain important components of supportive care. As the indication and the comorbidities for HCT continue to change, especially with older and more infirm patients, SOS remains an important area for clinicians. I discuss how SOS could be addressed, from prophylaxis to diagnosis and potential therapy.

引用

收藏

页码：4023 / 4026

页数：4

相关论文

共 61 条

[1]

ATTAL M, 1992, BLOOD, V79, P2834

[2]

MODULATION OF ENDOTHELIAL AND PLATELET-FUNCTION BY A POLYDEOXYRIBONUCLEOTIDE DERIVED DRUG DEFIBROTIDE - A DUAL MECHANISM IN THE CONTROL OF VASCULAR PATHOLOGY [J].

BACHER, P ;

KINDEL, G ;

WALENGA, JM ;

FAREED, J .

THROMBOSIS RESEARCH, 1993, 70 (04) :343-348

[3]

VENOOCCLUSIVE DISEASE OF THE LIVER - DEVELOPMENT OF A MODEL FOR PREDICTING FATAL OUTCOME AFTER MARROW TRANSPLANTATION [J].

BEARMAN, SI ;

ANDERSON, GL ;

MORI, M ;

HINDS, MS ;

SHULMAN, HM ;

MCDONALD, GB .

JOURNAL OF CLINICAL ONCOLOGY, 1993, 11 (09) :1729-1736

[4]

Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease [J].

Benimetskaya, Luba ;

Wu, Sijian ;

Voskresenskiy, Anatoliy M. ;

Echart, Cinara ;

Zhou, Jin-Feng ;

Shin, Joongho ;

Iacobelli, Massimo ;

Richardson, Paul ;

Ayyanar, Kanyalakshmi ;

Stein, C. A. .

BLOOD, 2008, 112 (10) :4343-4352

[5]

DEFIBROTIDE, BY ENHANCING PROSTACYCLIN GENERATION, PREVENTS ENDOTHELIN-1 INDUCED CONTRACTION IN HUMAN SAPHENOUS VEINS [J].

BERTI, F ;

ROSSONI, G ;

BIASI, G ;

BUSCHI, A ;

MANDELLI, V ;

TONDO, C .

PROSTAGLANDINS, 1990, 40 (04) :337-350

[6]

Parenteral glutamine protects hepatic function during bone marrow transplantation [J].

Brown, SA ;

Goringe, A ;

Fegan, C ;

Davies, SV ;

Giddings, J ;

Whittaker, JA ;

Burnett, AK ;

Poynton, CH .

BONE MARROW TRANSPLANTATION, 1998, 22 (03) :281-284

[7]

Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan [J].

Cappelli, Barbara ;

Chiesa, Robert ;

Evangelio, Costanza ;

Biffi, Alessandra ;

Roccia, Tito ;

Frugnoli, Ilaria ;

Biral, Erika ;

Noe, Anna ;

Fossati, Marco ;

Finizio, Valentina ;

Miniero, Roberto ;

Napolitano, Sara ;

Ferrua, Francesca ;

Soliman, Clara ;

Ciceri, Fabio ;

Roncarolo, Maria G. ;

Marktel, Sarah .

BRITISH JOURNAL OF HAEMATOLOGY, 2009, 147 (04) :554-560

[8]

ON THE RELIABILITY OF CLINICAL-CRITERIA FOR THE DIAGNOSIS OF HEPATIC VENOOCCLUSIVE DISEASE [J].

CARRERAS, E ;

GRANENA, A ;

NAVASA, M ;

BRUGUERA, M ;

MARCO, V ;

SIERRA, J ;

TASSIES, MD ;

GARCIAPAGAN, JC ;

MARTI, JM ;

BOSCH, J ;

RODES, J ;

ROZMAN, C .

ANNALS OF HEMATOLOGY, 1993, 66 (02) :77-80

[9]

Prevention of veno-occlusive disease with defibrotide after allogeneic stem cell transplantation [J].

Chalandon, Y ;

Roosnek, E ;

Mermillod, B ;

Newton, A ;

Ozsahin, H ;

Wacker, P ;

Helg, C ;

Chapuis, B .

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2004, 10 (05) :347-354

[10]

Defibrotide for the treatment of hepatic veno-occlusive disease: results of the European compassionate-use study [J].

Chopra, R ;

Eaton, JD ;

Grassi, A ;

Potter, M ;

Shaw, B ;

Salat, C ;

Neumeister, P ;

Finazzi, G ;

Iacobelli, M ;

Bowyer, K ;

Prentice, HG ;

Barbui, T .

BRITISH JOURNAL OF HAEMATOLOGY, 2000, 111 (04) :1122-1129

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