PWMScan: a fast tool for scanning entire genomes with a position-specific weight matrix

被引：94

作者：

Ambrosini, Giovanna ^{[1
,2
]}

Groux, Romain ^{[1
,2
]}

Bucher, Philipp ^{[1
,2
]}

机构：

[1] Swiss Fed Inst Technol Lausanne EPFL, Swiss Inst Expt Canc Res ISREC, CH-1015 Lausanne, Switzerland

[2] Swiss Inst Bioinformat, CH-1015 Lausanne, Switzerland

来源：

BIOINFORMATICS | 2018年 / 34卷 / 14期

关键词：

D O I：

10.1093/bioinformatics/bty127

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A Summary: Transcription factors regulate gene expression by binding to specific short DNA sequences of 5-20 bp to regulate the rate of transcription of genetic information from DNA to messenger RNA. We present PWMScan, a fast web-based tool to scan server-resident genomes for matches to a user-supplied PWM or transcription factor binding site model from a public database.

引用

页码：2483 / 2484

页数：2

共 5 条

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